DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aldh-III and alh-11

DIOPT Version :9

Sequence 1:	NP_724562.2	Gene:	Aldh-III / 45398	FlyBaseID:	FBgn0010548	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001379574.1	Gene:	alh-11 / 185679	WormBaseID:	WBGene00000117	Length:	687	Species:	Caenorhabditis elegans

Alignment Length:	345	Identity:	105/345 - (30%)
Similarity:	165/345 - (47%)	Gaps:	30/345 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 PFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVC 233
            |.|||..|||||||:|......|.|:|.||.|:.|||.::...|..:|:::... |.:..:.|:
Worm   340 PVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPLSPVTALILAEILKSAGLPDGVFNVI- 403

  Fly   234 GGPSETAELL--NQRFDYIFYTGSTRVG-KIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAV 295
            .|.:|||:.|  :.....:.:|||...| ||:.|.|::.:.|.||||||||...:....|:.:||
Worm   404 QGDAETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIKPVTLELGGKSALIVFDDADIDSAV 468

  Fly   296 KRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKD-VLKEWYGENIQSSPDLSRVINANNFQR 359
            ...:.....:.||.|.....:|..|.|.::|..:..| ..|...|:.::....:...|:|.:..:
Worm   469 SCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVDHTQKMKIGDPLKEDTQVGSHISAEHRNK 533

  Fly   360 LLGLMKSG------------RVAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVE 412
            :.|.:.:.            ||||.|..:..  ::.|.||..:.....:..|||||.:|.|...:
Worm   534 VEGYISTAIAEGATKLCGGDRVAVHGLENGF--YLSPCILTGITPKMTVYREEIFGSVLLIIPFD 596

  Fly   413 SAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRS-TTSGGFSSNETIMHCGVDV---LPFGGVGM 473
            :..:|||..|..:..|.      :..:.|:..|| ..|...::....::...||   :||||||.
Worm   597 TEDEAIKIANDTDMGLA------AGLVTKDLSRSYRVSEQLNAGNVYVNTYNDVSPLVPFGGVGE 655

  Fly   474 SGMGRYHGKYGFETFTHKKS 493
            ||.||.:|....|.:||.||
Worm   656 SGFGRENGTAVLEHYTHLKS 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	105/345 (30%)
alh-11	NP_001379574.1	NLPC_P60	<30..131	CDD:419716
alh-11	NP_001379574.1	ALDH_F9_TMBADH	225..681	CDD:143409	105/345 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910