Protein Alignment Aldh-III and alh-4

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001360568.1
• Gene: alh-4 / 179026
• WormBaseID: WBGene00000110
• Length: 495
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 215/497 - (43%)
• Similarity: 310/497 - (62%)
• Gaps: 14/497 - (2%)

  Fly    70 FDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMK 134
            |.:.::..|..|.:|:|:.|.||::||..|.:..||:...:..|:..||||..:.:.|:|.....
 Worm     3 FTELVETQRKYFRTGETKPVKFRKQQLLKLKKFIEENREALSEAVWKDLRRRHESTEILEIGMTI 67

  Fly   135 NDIRHILFQLDEWVQSEKPPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGN 199
            .:|.:.|..:|:||:.....|:|...:|...|..||.||||:|..||||:.::|:|:..||||||
 Worm    68 QEIDYFLKNIDDWVKPTHVEKTFTTALDKPVIEKDPKGVVLIISPWNYPVSMILLPMVPAIAAGN 132

  Fly   200 CVVIKPSEIAANCAKFIADVIPKYLDNDCYPVVCGGPSETAELLNQRFDYIFYTGSTRVGKIIHA 264
            .|||||||::.|.|.....:||||.::....||.||..||.:||.:|||:|.|||...|.|||..
 Worm   133 TVVIKPSELSENVAATFEKLIPKYFESKYVTVVNGGIPETTDLLKERFDHILYTGCPPVAKIIMT 197

  Fly   265 AANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVE 329
            ||.|:|||.|||||||.|..::...|:..:.|||.|||.:||||||:||||||.:..|:.|.:..
 Worm   198 AAAKHLTPVTLELGGKCPVVVEDDADIDISAKRIAWGKWLNCGQTCLAPDYILVNSTVKPKLVAA 262

  Fly   330 AKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLM--KSGRVAVGGNYDASERFIEPTILVDVKE 392
            .:..:.|:|||::::|.|.:|:||..:|.|:.||:  ..|.|.:||..|.::.:|.||:| ||::
 Worm   263 IRKYVNEFYGEDVKASKDYARMINQRHFDRISGLLDKTQGAVLIGGERDRADLYIPPTVL-DVEK 326

  Fly   393 TDPIMEEEIFGPILPIFNVESAYDAIKFINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNET 457
            :||.|.:|||||:|||..|:|..:::::|...||||..|:|:.:...||.....|:|||.:.|:.
 Worm   327 SDPFMHDEIFGPVLPIITVQSFSESLEYIADGEKPLAAYIFTRNEAKVKRLLNETSSGGVTVNDV 391

  Fly   458 IMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLL 522
            :||..||.|||||||:||||||.|||||:||||:||.|.:..  .||.|.:|||||.|.:|...:
 Worm   392 LMHITVDTLPFGGVGVSGMGRYRGKYGFDTFTHEKSVLHRGF--FGESLLAARYPPLSQQKLDQM 454

  Fly   523 SFLLRKRRPLPNLHLSHVLAIGLGVGLTVLTNYYLQGKLLSK 564
            ..|..||   .:|:|.:|..      |.::...::.|.|..|
 Worm   455 RRLTGKR---ISLNLMNVAT------LPIVMASFVFGMLFQK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	202/444 (45%)
alh-4	NP_001360568.1	ALDH_F3-13-14_CALDH-like	5..430	CDD:143406	193/425 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	390	1.000	Domainoid score	I406
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	409	1.000	Inparanoid score	I1055
Isobase	1	0.950	-	0	Normalized mean entropy	S1337
OMA	1	1.010	-	-		QHG62894
OrthoDB	1	1.010	-	-		D225045at33208
OrthoFinder	1	1.000	-	-		FOG0000656
OrthoInspector	1	1.000	-	-		otm14355
orthoMCL	1	0.900	-	-		OOG6_100557
Panther	1	1.100	-	-	LDO	PTHR43570
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2145
SonicParanoid	1	1.000	-	-		X395
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.960