Protein Alignment Aldh-III and alh-3

DIOPT Version :10

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_502054.2
• Gene: alh-3 / 177999
• WormBaseID: WBGene00000109
• Length: 908
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 137/535 - (25%)
• Similarity: 222/535 - (41%)
• Gaps: 107/535 - (20%)

  Fly     8 PHPE-ANGAPINAAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFD 71
            ||.: .:|..:.::..|...|:     .|.||.||                  .|.....:|:.|
 Worm   427 PHDQFIDGKFVGSSDGRTFKTI-----NPATEKPI------------------CELPLATVADVD 468

  Fly    72 DTLQRARLAFSSGKTRNVSFRR--KQLENLLRCYEEHENEI--ISALEADLRRPKQESLIVETEF 132
            ..::.|:.||..|:.|.:|.|.  |:|..|....|||:.|:  :.:|:|.         .|.|..
 Worm   469 RAVRAAKKAFERGEWRQMSARERGKRLYKLAELMEEHKEELATLESLDAG---------AVYTLA 524

  Fly   133 MKNDIRHILFQLDEWVQSEKPPKSFVNMMDDVQ-----IYN------------DPFGVVLVIGAW 180
            :|.   |:...:|.|       :.|....|.:|     |.|            :|.|||.:|..|
 Worm   525 LKT---HVGMSIDVW-------RYFAGWCDKIQGKTIPISNARPNKNLCLTLREPIGVVGLITPW 579

  Fly   181 NYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADV-----IPKYLDNDCYPVVCGGPSETA 240
            ||||.:|...:|:.:||||.||.||:::....|...|::     ||..:.|    :|.|..|...
 Worm   580 NYPLMMLSWKMAACLAAGNTVVHKPAQVTPLTALKFAELSVLAGIPPGVIN----IVTGSGSLVG 640

  Fly   241 ELLNQRFDY--IFYTGSTRVG-KIIHAAANKYLTPTTLELGGKSPCYIDKSVDMRTAVKRILWGK 302
            ..|....|.  |.:||||.:| .::.:.|...:...:||||||||..|....|:..|||:.....
 Worm   641 NRLTAHPDVRKIGFTGSTEIGATVMESCAKSNIKKVSLELGGKSPLIIFADADLEKAVKQACGAV 705

  Fly   303 LINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEW-YGENIQSSPDLSRVINANNFQRLLGLMK- 365
            ..|.|:.|||...:..:|.:.:.|:.:..:..|:: .|:.:..|.......:..:..:|:..::
 Worm   706 FFNKGENCIAAGRVFIAKSIHDDFVKKLVEEAKQYQIGDPLDRSTAHGPQNHLAHLNKLVEYVEK 770

  Fly   366 ----SGRVAVGG-NYDASERFIEPTILVDVKETDPIMEEEIFGPILPI--FNVESAYDAIKFINA 423
                ..:|.||| ..:....:..||||.::.:.:....||.||||:.:  |:.:...|.::..|.
 Worm   771 AVAGGAKVEVGGKRLEREGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRAND 835

  Fly   424 REKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCG---------VDV-LPFGGVGMSGMGR 478
            .|..|...||:..:.  |..|.:..          :|.|         .|| .||||...||.|:
 Worm   836 TEFGLAAGVFTRDSS--KSLRVAEA----------LHAGTVFVNTYQKTDVAAPFGGFKQSGFGK 888

  Fly   479 YHGKYGFETFTHKKS 493
            ..|:.....:...|:
 Worm   889 DMGEEALNEYLVTKT 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	124/470 (26%)
alh-3	NP_502054.2	FMT_core_FDH_N	1..209	CDD:187716
		FDH_Hydrolase_C	214..315	CDD:187731
		PP-binding	335..393	CDD:425746
		ALDH-SF	423..908	CDD:448367	137/535 (26%)