Protein Alignment Aldh-III and Aldh1a1

DIOPT Version :9

• Sequence 1: NP_724562.2
• Gene: Aldh-III / 45398
• FlyBaseID: FBgn0010548
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001348432.1
• Gene: Aldh1a1 / 11668
• MGIID: 1353450
• Length: 501
• Species: Mus musculus
• Alignment Length: 476
• Identity: 131/476 - (27%)
• Similarity: 213/476 - (44%)
• Gaps: 68/476 - (14%)

  Fly    56 EQLQSESESDRMANFDDTLQRARLAFSSG---KTRNVSFRRKQLENLLRCYEEHENEIISALEAD 117
            |::....|....|:.|..::.||.||..|   :|.:.| .|.:|.|.|....|.:..:::.:||
Mouse    46 EEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDAS-ERGRLLNKLADLMERDRLLLATMEA- 108

  Fly   118 LRRPKQESLIVETEFMKNDIRHILFQLD---EWVQSEKPPKSFVNMMDDVQIY--NDPFGVVLVI 177
            |...|     |......:|:...:..|.   .|  ::|.....:....|:..|  .:|.||...|
Mouse   109 LNGGK-----VFANAYLSDLGGCIKALKYCAGW--ADKIHGQTIPSDGDIFTYTRREPIGVCGQI 166

  Fly   178 GAWNYPLQLLLVPVASAIAAGNCVVIKPSE----IAANCAKFI---------ADVIPKYLDNDCY 229
            ..||:|:.:.:..:..|::.||.||:||:|    .|.:.|..|         .:::|.|
Mouse   167 IPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGY------ 225

  Fly   230 PVVCGGPSETAELLNQR-FDYIFYTGSTRVGKIIHAAANK-YLTPTTLELGGKSPCYIDKSVDMR 292
                 ||:..|.:.:.. .|.:.:||||:|||:|..||.| .|...||||||||||.:....|:.
Mouse   226 -----GPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLD 285

  Fly   293 TAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGEN-----IQSSPDLSRVI 352
            .||:....|...:.||.|:|...|...:.|.::|:..:.:..|::...|     |...|.    |
Mouse   286 IAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVKRSVERAKKYVLGNPLTPGINQGPQ----I 346

  Fly   353 NANNFQRLLGLMKSGR------VAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNV 411
            :.....::|.|::||:      ...||.:.....|::||:..:|.:...|.:||||||:..|...
Mouse   347 DKEQHDKILDLIESGKKEGAKLECGGGRWGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKF 411

  Fly   412 ESAYDAIKFINAREKPLVIYVFSNS-NKLVKEFRRSTTSGGFSSNETIMHCGVDV---LPFGGVG 472
            :|..|.||..|.....|...:|:.. :|.:      |.|....:....::|.:.:   .||||..
Mouse   412 KSVDDVIKRANNTTYGLAAGLFTKDLDKAI------TVSSALQAGVVWVNCYMMLSAQCPFGGFK 470

  Fly   473 MSGMGRYHGKYGFETFTHKKS 493
            |||.||..|::|...:|..|:
Mouse   471 MSGNGRELGEHGLYEYTELKT 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aldh-III	NP_724562.2	ALDH_F3AB	72..515	CDD:143450	127/460 (28%)
Aldh1a1	NP_001348432.1	ALDH_F1AB_F2_RALDH1	15..495	CDD:143459	131/476 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810