Protein Alignment E5 and Nkx6-3

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001102925.1
• Gene: Nkx6-3 / 685102
• RGDID: 1597780
• Length: 262
• Species: Rattus norvegicus
• Alignment Length: 252
• Identity: 74/252 - (29%)
• Similarity: 93/252 - (36%)
• Gaps: 67/252 - (26%)

  Fly   198 AQF-QMAAALAHHHQQQQQQQQQQLPPVPTGP------PHG-----PHPHLPPGQIPLGIFPGGP 250
            ||| :|.|.:.   |...|....:|.|...||      |||     ..|...|..   .:..|.|
  Rat    17 AQFSEMKAPMC---QYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVATPNS---SLLSGYP 75

  Fly   251 HPGHPPPHGHHPFGSAPHLIRDSYPLY--PWL--LSRHGRIFPRFPGNF---------------- 295
            |..        .||..     .|..:|  |.:  .|:.|..:|....|.
  Rat    76 HVA--------GFGGL-----SSQGVYYGPQVGSFSKTGNEYPTRTRNCWADTGQDWRGSTRPCS 127

  Fly   296 -----LFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRR 355
                 |.....|.|..|..|:..|:..||..||...|:.|.||.:||..|.:||:||||||||||
  Rat   128 NTPDPLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRR 192

  Fly   356 TK-HKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDPEDEDE 411
            || .|:...|  ..|.|....|.:||.....:.|||        .|....||:.:||
  Rat   193 TKWRKKSALE--PSSSTPRAPGGASGDRAASENEDD--------EYNKPLDPDSDDE 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	29/56 (52%)
Nkx6-3	NP_001102925.1	Homeodomain	139..197	CDD:459649	30/57 (53%)