Protein Alignment E5 and nkx6.2

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001129256.1
• Gene: nkx6.2 / 565782
• ZFINID: ZDB-GENE-070626-1
• Length: 278
• Species: Danio rerio
• Alignment Length: 225
• Identity: 66/225 - (29%)
• Similarity: 91/225 - (40%)
• Gaps: 56/225 - (24%)

  Fly   224 VPTGPPHG-----PHPHLPPGQIPLGIFP--------GGPH--PG----HPPPHGHHPFGSAPHL 269
            :|.|.|||     ..|....||:..| ||        .|.:  |.    :|.|....| |.||..
Zfish    58 IPLGTPHGISDILGRPITTAGQLLSG-FPRINGLATSAGMYFNPAAVSRYPKPLTELP-GRAPIF 120

  Fly   270 IRDSYPLYPWLLSRHGRIFPRFP----GNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVG 330
            ........||.       .||.|    .|.:.....|.|..|..||..|:..||..||...|:.|
Zfish   121 WPGMMQGSPWR-------DPRVPCAAQANMMLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAG 178

  Fly   331 AERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDG 395
            .||.:||..|.:||:||||||||||||.::  :...:.:..|.                  |||.
Zfish   179 PERARLAYSLGMTESQVKVWFQNRRTKWRK--RHAAEMATAKK------------------KHDS 223

  Fly   396 SQHSYEDAEDPEDEDE----IEEDDEDEVI 421
            .....:::.|.:::||    ::.:.:||.|
Zfish   224 ETEKMKESSDNDEDDEYNKPLDPNSDDEKI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	30/55 (55%)
nkx6.2	NP_001129256.1	Homeodomain	150..208	CDD:459649	31/57 (54%)