Protein Alignment E5 and nkx6.3

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001159612.1
• Gene: nkx6.3 / 558978
• ZFINID: ZDB-GENE-070810-7
• Length: 272
• Species: Danio rerio
• Alignment Length: 226
• Identity: 69/226 - (30%)
• Similarity: 93/226 - (41%)
• Gaps: 67/226 - (29%)

  Fly   227 GPPHGPHPHLPPGQIPLGIFPGGPH--PGHPPPHGHHPFGS---AP--HLIRDSYPL-------- 276
            |.|||....|....:.   .||.|.  .|:|...|   ||:   :|  :..||..|.
Zfish    50 GTPHGISDILSRSMVS---GPGTPALLSGYPSMGG---FGTTVPSPGVYYNRDYTPSGLSTFPKP 108

  Fly   277 -------------------YPWLLSRH--GRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEH 320
                               |.|..:|.  |......|.|     ..|.|..|..||..|:..||.
Zfish   109 VVECAGMKGKSSSCWVDGGYEWRGARQQCGNNMGHNPEN-----VGKKKHTRPTFSGHQIFALEK 168

  Fly   321 AFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGG 385
            .||...|:.|.||.:||..|.:||:||||||||||||.::  :...:.|.|::::|.|:|
Zfish   169 TFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK--KSATEPSSTQTSRGESAG----- 226

  Fly   386 DGEDDAKHDGSQHSYEDAE-----DPEDEDE 411
                    |||::..||.|     ||:.:||
Zfish   227 --------DGSENEVEDEEYNKPLDPDTDDE 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	30/55 (55%)
nkx6.3	NP_001159612.1	Homeodomain	150..208	CDD:459649	31/57 (54%)