Protein Alignment E5 and HGTX

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 116/494 - (23%)
• Similarity: 162/494 - (32%)
• Gaps: 165/494 - (33%)

  Fly    26 SVAASSTSVSASSTVSASASSKPKLAFS----IDS-----IVGESSTRSAPLRVSVISSPPPRSE 81
            |.:.|:|...|||.:.:.:|..|:...:    :||     :...||....|.:.|..:||||:.:
  Fly   176 SDSPSTTPPPASSRLHSDSSPSPRYEHNSSPGVDSAKSYALSQRSSGAEDPCQTSESASPPPQGQ 240

  Fly    82 SPASPTNTNNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPS 146
            :..||.|.                        |.||:....     :.|.||.|..|...:|:|.
  Fly   241 NDYSPENL------------------------SSQRAKFQH-----HHGVNPLALHNANHAGNPG 276

  Fly   147 SGTGN-------PPTLIRPLPLPA----------------------------PNLALIGNR---- 172
            ....|       |.:.:.| ||.|                            ||..||.:|
  Fly   277 CHNNNNHMDHKLPLSFLGP-PLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDRGSGG 340

  Fly   173 ----TSPNAMAVRMAGPPHPP------SQPPPFLAA-----------QFQMAAALAHHHQQQQQQ 216
                :|.........|.|:|.      |:|||..:|           :|.:|||.|   ...|..
  Fly   341 SSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAA---GMAQYL 402

  Fly   217 QQQQLPPVPTGPPHGPH----PHLP-PGQIPLGIFP--------GGPHPGHPPPHGHHPFGSAPH 268
            .|.|..|:.|   |..|    .||. ||...|...|        ..........|.|||...
  Fly   403 SQSQGAPLKT---HAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSND--- 461

  Fly   269 LIRDSYPLYPWLLSRHGRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAER 333
              :|.                            |.|..|..||..|:..||..||...|:.|.||
  Fly   462 --KDG----------------------------KKKHTRPTFSGQQIFALEKTFEQTKYLAGPER 496

  Fly   334 KQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQH 398
            .:||..|.::|:||||||||||||.::..     .::..:.|......||..||:.....|....
  Fly   497 AKLAYALGMSESQVKVWFQNRRTKWRKRH-----AAEMATAKRKQDDMGGDNDGDCSETMDSDNE 556

  Fly   399 SYEDAEDPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQR 437
            |.:..|.|........:..         ||....:::.|
  Fly   557 SLDMGESPAQNKRCRSNSS---------GSSQQQQDNYR 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	29/55 (53%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	50/238 (21%)
		Homeodomain	465..523	CDD:459649	30/57 (53%)