Protein Alignment E5 and MSX2

DIOPT Version :9

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 65/250 - (26%)
• Similarity: 90/250 - (36%)
• Gaps: 59/250 - (23%)

  Fly   123 SPSPPNAGGNPAAAGNTAKSGDPSSGTGN-----PPTLIRPLPLPAPNLALIGNRTSPNAMAVRM 182
            |||..|...:|...|....:| |..|.|.     ....::...||....||:.::
Human     3 SPSKGNDLFSPDEEGPAVVAG-PGPGPGGAEGAAEERRVKVSSLPFSVEALMSDK---------- 56

  Fly   183 AGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFP 247
                .||.:..|..|......|.|.                                  ||.:..
Human    57 ----KPPKEASPLPAESASAGATLR----------------------------------PLLLSG 83

  Fly   248 GGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIFP----RFPGNFLFQPFRKPKRVRT 308
            .|....|.|.....||.:|.....:|.....| :...||..|    ..|.....:..:..::.||
Human    84 HGAREAHSPGPLVKPFETASVKSENSEDGAAW-MQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRT 147

  Fly   309 AFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQ 363
            .|:.:|||.||..|....|:..|||.:.:..|:|||||||:||||||.|.||:|:
Human   148 PFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	28/51 (55%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		18/82 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		4/30 (13%)
		Homeobox	145..199	CDD:365835	28/53 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810