Protein Alignment E5 and MSX1

DIOPT Version :9

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 81/259 - (31%)
• Similarity: 101/259 - (38%)
• Gaps: 69/259 - (26%)

  Fly   124 PSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAGPPHP 188
            |:...||..|:||..||.:.........|.  :.|..||....||:.:...|.|....:|
Human    24 PAGGGAGQAPSAAAATAAAMGADEEGAKPK--VSPSLLPFSVEALMADHRKPGAKESALA----- 81

  Fly   189 PSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPH-P 252
            ||:       ..|.|...|.                |.|        :|||.:      |.|. |
Human    82 PSE-------GVQAAGGSAQ----------------PLG--------VPPGSL------GAPDAP 109

  Fly   253 GHPPPHGHHPFGSAPHLIRDSY---------PLYPWLLSRHGRIFPRF---PGNFLFQP---FRK 302
            ..|.|.||...|....|..|:.         ...||:.|      |||   |...|..|   .||
Human   110 SSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQS------PRFSPPPARRLSPPACTLRK 168

  Fly   303 PK---RVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQ 363
            .|   :.||.|:..|||.||..|....|:..|||.:.:..|||||||||:||||||.|.||:|:
Human   169 HKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQE 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	29/51 (57%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		9/32 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		18/89 (20%)
		PTZ00449	<105..>248	CDD:185628	53/134 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		12/46 (26%)
		Homeobox	175..229	CDD:395001	29/53 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810