DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E5 and emx1

DIOPT Version :9

Sequence 1:	NP_524825.1	Gene:	E5 / 45396	FlyBaseID:	FBgn0008646	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001005459.1	Gene:	emx1 / 448058	XenbaseID:	XB-GENE-920144	Length:	233	Species:	Xenopus tropicalis

Alignment Length:	209	Identity:	95/209 - (45%)
Similarity:	116/209 - (55%)	Gaps:	38/209 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 VRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLG 244
            :|.|..|:|.:....|::. |...|..:.::     ..:...|...:.||...|||    |:
Frog    28 LRPAALPYPGAPAEAFVSG-FPSPAGRSLYN-----NPELVFPETVSHPPLTVHPH----QL--- 79

  Fly   245 IFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIF-PRFPGN-------FLFQPF- 300
               |..|..||     |.|.:..|  ||....|||:|  ..|.| .||.|.       .|..||
Frog    80 ---GASHLQHP-----HSFFAPQH--RDPLNFYPWVL--RNRFFGHRFQGGDVSQESLLLHGPFA 132

  Fly   301 RKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKR--MQQ 363
            |||||:||||||:|||:||.|||.|||||||||||||..|||:||||||||||||||:||  :::
Frog   133 RKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLASSLSLSETQVKVWFQNRRTKYKRQKLEE 197

  Fly   364 EGGDGSDTKSNKGS 377
            ||.| ||.| .|||
Frog   198 EGPD-SDQK-KKGS 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	44/51 (86%)
emx1	NP_001005459.1	COG5576	85..>194	CDD:227863	70/117 (60%)
		Homeobox	139..192	CDD:365835	44/52 (85%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..233		10/20 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6622
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000921
OrthoInspector	1	1.000	-	-		mtm9445
Panther	1	1.100	-	-	LDO	PTHR24339
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3162
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.040