Protein Alignment E5 and abd-A

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 671
• Identity: 142/671 - (21%)
• Similarity: 188/671 - (28%)
• Gaps: 343/671 - (51%)

  Fly    10 NMLPMAP------------TSPFVSSSSSVAA--SSTSVSASSTVSASASSKPKLAFSIDSIVGE 60
            :|||..|            |:|..|||::|||  ::.:.|||::||||:||...   |.::|.|.
  Fly     8 SMLPKYPQFQPFISSHHLTTTPPNSSSAAVAAALAAAAASASASVSASSSSNNN---SSNTIAGS 69

  Fly    61 SSTRSAPLRVSVISSPPPRSESPASPTNTNNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPS 125
            ::                        :|||||
  Fly    70 NT------------------------SNTNNS--------------------------------- 77

  Fly   126 PPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAGPPHPP- 189
                            |..|||.:.|           ..||.|.|...||:.::..:...||.|
  Fly    78 ----------------SSSPSSSSNN-----------NSNLNLSGGSLSPSHLSQHLGQSPHSPV 115

  Fly   190 SQPPPFLAAQFQMAAA-LAH------HHQQQQ--------------QQQQQQLPPVPTG--PPHG 231
            |...||.....|:... |.|      ||||||              ||||..:..:...  ..||
  Fly   116 SSSSPFQQHHPQVQQQHLNHQQQQHLHHQQQQHHHQYSSLSAALQLQQQQHHISKLAAAAVASHG 180

  Fly   232 PHPH-----LPP--GQIPLGIFPGGPHP------------------------------------- 252
             |.|     .||  |....|.....|.|
  Fly   181 -HAHQQLLLTPPSAGNSQAGDSSCSPSPSASGSSSLHRSLNDNSPGSASASASASAASSVAAAAA 244

  Fly   253 ----------------------GHPPPHG------------------------------------ 259
                                  .||..||
  Fly   245 AAAAAASSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDKSCSRYTDTVMNSYQSMSVPASA 309

  Fly   260 --------HHPFGSAPHLIRDS----------------------------------YPLYPW--L 280
                    .|...:|..:...|                                  .|.|||  |
  Fly   310 SAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASGVMPGAGGAGGAGIADLPRYPWMTL 374

  Fly   281 LSRHGRIFPRFP-GNFLFQ---PFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLS 341
            ....|..|.|.. |:|...   |.|:.::..|.|   |.|:||..|..|||:....|.::|..|.
  Fly   375 TDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRF---QTLELEKEFHFNHYLTRRRRIEIAHALC 436

  Fly   342 LTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDP 406
            |||.|:|:||||||.|.|:         :.::.|
  Fly   437 LTERQIKIWFQNRRMKLKK---------ELRAVK------------------------------- 461

  Fly   407 EDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQ 471
                ||.|.            :..|.||.::::.|...:.||..:|..||        ..|||.|
  Fly   462 ----EINEQ------------ARRDREEQEKMKAQETMKSAQQNKQVQQQ--------QQQQQQQ 502

  Fly   472 LLQQHQQHLQQQHHQQQQHFI 492
            ..||.|||.|||...|..|.|
  Fly   503 QQQQQQQHQQQQQQPQDHHSI 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	25/55 (45%)
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	26/58 (45%)
		Abdominal-A	456..478	CDD:403567	7/68 (10%)