Protein Alignment E5 and cdx2

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_989209.1
• Gene: cdx2 / 394817
• XenbaseID: XB-GENE-483306
• Length: 252
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 75/312 - (24%)
• Similarity: 101/312 - (32%)
• Gaps: 122/312 - (39%)

  Fly   102 YCRRRDSLDRSRSPQRSP-VSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPN 165
            |...:|:.....|.:..| :...|:.|......:..|.....|.||||:
 Frog     5 YLLEKDAAMYPGSMRAHPGLQNYPAAPQYPDYGSYHGMGLDHGAPSSGS---------------- 53

  Fly   166 LALIGNRTSPNAMAVRMAGPP------HPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPV 224
                      :|..:...|||      ||...|              .|.|          :.|.
 Frog    54 ----------SAGWITPYGPPRDEWGVHPTYSP--------------GHTH----------INPS 84

  Fly   225 PTG-----PPHGPHPHLPPGQIPLGIFPGGP----HPGHPPPHGHHPFGSAPHLIRDSYPLYPWL 280
            |.|     |.:.|..  ..||..:|:.|.||    .||....|..|      |        |.||
 Frog    85 PVGNMAFSPDYSPAQ--VQGQPCVGVLPAGPPPQLSPGSEDGHRRH------H--------YEWL 133

  Fly   281 LSRHGRIFPRFPGNFLFQPFRKP-------------KRVRTAFSPTQLLKLEHAFEGNHYVVGAE 332
                                |||             .:.|..::..|.|:||..|..:.|:....
 Frog   134 --------------------RKPVSQASTGSKTRTKDKYRVVYTDQQRLELEKEFHYSRYITIRR 178

  Fly   333 RKQLAQGLSLTETQVKVWFQNRRTKH-----KRMQ--QEGGDGSDTKSNKGS 377
            :.:||..|.|:|.|||:||||||.|.     ||:|  |.|.:|.||.|.:.|
 Frog   179 KAELAANLGLSERQVKIWFQNRRAKERKITKKRIQQTQTGQNGPDTLSPEPS 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	22/60 (37%)
cdx2	NP_989209.1	Caudal_act	13..143	CDD:461413	41/215 (19%)
		Homeodomain	151..206	CDD:459649	22/54 (41%)