Protein Alignment E5 and Hoxd12

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001178832.1
• Gene: Hoxd12 / 366082
• RGDID: 1309797
• Length: 268
• Species: Rattus norvegicus
• Alignment Length: 284
• Identity: 64/284 - (22%)
• Similarity: 98/284 - (34%)
• Gaps: 94/284 - (33%)

  Fly   108 SLDRSRSP-QRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGN 171
            |..||..| ..:|.|.:|:.|...   :|.|..::.....||         |:.|.:|     |.
  Rat    43 SYPRSALPWAATPASCTPAQPTTA---SAFGGFSQPYLTGSG---------PIGLQSP-----GT 90

  Fly   172 RTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHL 236
            :..|... |:...|.                 ||.|...:.:            |.||..|...|
  Rat    91 KDGPEDQ-VKFYTPD-----------------AATASEERSR------------TRPPFAPESSL 125

  Fly   237 ------------------PPGQIPLGIFPGGPHPGHPPPHGHHPF--------GSAPHLIRDSYP 275
                              .||.:.|  ..|.|...:.......|.        ......:|.|.|
  Rat   126 VHSALKGTKYDFAGVGRAAPGSVTL--LQGAPCASNFKEDTKGPLNLNMAVQVAGVASCLRSSLP 188

  Fly   276 -LYPWLLSRHGRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQG 339
             ..||..:         ||        :.::.|..::..|:.:||:.|..|.::...:||:|:..
  Rat   189 DGLPWGAA---------PG--------RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNR 236

  Fly   340 LSLTETQVKVWFQNRRTKHKRMQQ 363
            |:|::.|||:||||||.|.||:.|
  Rat   237 LNLSDQQVKIWFQNRRMKKKRVVQ 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	21/55 (38%)
Hoxd12	NP_001178832.1	Homeodomain	201..257	CDD:459649	21/55 (38%)