Protein Alignment E5 and HOXC6

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_004494.1
• Gene: HOXC6 / 3223
• HGNCID: 5128
• Length: 235
• Species: Homo sapiens
• Alignment Length: 148
• Identity: 46/148 - (31%)
• Similarity: 71/148 - (47%)
• Gaps: 25/148 - (16%)

  Fly   265 SAPHLIRDSYPLYPWL--LSRHGRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHY 327
            :||...:.|..:|||:  ::.|..:.        :...|  :|.|..:|..|.|:||..|..|.|
Human   111 TAPQDQKASIQIYPWMQRMNSHSGVG--------YGADR--RRGRQIYSRYQTLELEKEFHFNRY 165

  Fly   328 VVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAK 392
            :....|.::|..|.|||.|:|:||||||.|.|:           :||..|:..|||||...|..
Human   166 LTRRRRIEIANALCLTERQIKIWFQNRRMKWKK-----------ESNLTSTLSGGGGGATADSL- 218

  Fly   393 HDGSQHSYEDAEDPEDED 410
             .|.:...|:.|:.:.::
Human   219 -GGKEEKREETEEEKQKE 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	25/55 (45%)
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		3/4 (75%)
		Homeodomain	142..198	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..235		12/36 (33%)