Protein Alignment E5 and HOXB8

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 55/232 - (23%)
• Similarity: 79/232 - (34%)
• Gaps: 93/232 - (40%)

  Fly   249 GPHPG----HPPP-----HGHHPFGSAPHLIRDSYPLYPWLLSRHGRIFPRFPGNF--------- 295
            ||..|    ||..     ||.....:||      |...|..::.||.     ||||
Human    41 GPSSGGSFQHPSQIQEFYHGPSSLSTAP------YQQNPCAVACHGD-----PGNFYGYDPLQRQ 94

  Fly   296 ---------------------------------------LFQPFRKP------KRVRTAFSPTQL 315
                                                   || |:.:|      :|.|..:|..|.
Human    95 SLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLF-PWMRPQAAAGRRRGRQTYSRYQT 158

  Fly   316 LKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSG 380
            |:||..|..|.|:....|.:::..|.|||.|||:||||||.|.|:         :...:|..||
Human   159 LELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK---------ENNKDKFPSS- 213

  Fly   381 GGGGGDGEDDAKHDGSQHSYEDAEDPEDEDEIEEDDE 417
                    ...:.:..:...|.|.:..||.:.::.|:
Human   214 --------KCEQEELEKQKLERAPEAADEGDAQKGDK 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	25/55 (45%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		3/5 (60%)
		Homeodomain	147..203	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		8/58 (14%)