Protein Alignment E5 and HOXA13

DIOPT Version :9

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_000513.2
• Gene: HOXA13 / 3209
• HGNCID: 5102
• Length: 388
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 91/399 - (22%)
• Similarity: 152/399 - (38%)
• Gaps: 122/399 - (30%)

  Fly    28 AASSTSVSASSTVSASASSKPKLA-------FSIDSIVGESSTRSAPLRVSVISSPPPRSESPAS 85
            ||::.:.:|::...|.....|..|       ||:.:....::..:|....::::.|.|.:...||
Human    39 AAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAAS 103

  Fly    86 PTNTNNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTG 150
                         .|           |.:|       ..:||:|....|||...|.:...:|.:|
Human   104 -------------AY-----------SSAP-------GEAPPSAAAAAAAAAAAAAAAAAASSSG 137

  Fly   151 NPPTLIRPLPLPA-PNLALIGNRTSP-NAMAVRMAGP-------------------PHPP----- 189
            .|.        || |..|....:.|| :|.|...:||                   |||.
Human   138 GPG--------PAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSC 194

  Fly   190 SQPPPFLAAQFQMAAALAHHHQ-------QQQQQQQQQLPPVPTGPPHGP-HPHLP-PGQIPLGI 245
            :||     |....|||.|..:.       ::...:.::......|...|| |.|.| ||.:.:.:
Human   195 AQP-----ASAAAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPV 254

  Fly   246 FPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSR--HGRIF-PRFPGNFLFQP-------- 299
            .||   .|.|....|.|.|    |..:||  .||.|..  :|::: |:...    ||
Human   255 VPG---LGGPGESRHEPLG----LPMESY--QPWALPNGWNGQMYCPKEQA----QPPHLWKSTL 306

  Fly   300 ------------FRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQ 352
                        :|:.::.|..::..||.:||..:..|.::...:|::::...:|:|.||.:|||
Human   307 PDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQ 371

  Fly   353 NRRTKHKRM 361
            |||.|.|::
Human   372 NRRVKEKKV 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	18/51 (35%)
HOXA13	NP_000513.2	HoxA13_N	85..222	CDD:403486	37/180 (21%)
		Homeobox	325..379	CDD:395001	18/53 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910