Protein Alignment E5 and Vsx1

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 661
• Identity: 144/661 - (21%)
• Similarity: 205/661 - (31%)
• Gaps: 260/661 - (39%)

  Fly     4 CGRQTFNMLPMAPTSPFVSSSSSVAASSTSVSAS-----STVSASA----------SSKPKLAFS 53
            |....||     |.:.:.::..:.||...:.:|:     :|::|:|          |:..:....
  Fly   112 CQLPVFN-----PANFYAAAGYAAAADPGNAAAAHHHHMTTLAAAAYLRGFLPPGFSTPHEFRGH 171

  Fly    54 IDSIVGESSTRSAPLR----VSVISSPPPRSESPASPTNTNNSGRRTPRGYIYCRRRDSLDRSRS 114
            .....|......|..|    .|.:::.....:||:..::::.:|.....|            |.|
  Fly   172 FQQHFGAQFAEQAAARGQEYASSLANASGDEQSPSKNSSSSGNGGSGGSG------------SGS 224

  Fly   115 PQRSPVSR------SPSPPNAG-----GNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLAL 168
            ...:|.|.      ||:..|.|     |...:.|.:..||..||.:||           ..|...
  Fly   225 GGGNPTSNGLGHLGSPTASNGGSGGGAGVGGSGGGSGTSGSNSSTSGN-----------GGNGGS 278

  Fly   169 IGNRTSPNAMAVRMAGPPHPPSQPPPFLAA--QFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHG 231
            .|:|:||       |||.|..:     |||  ....|||.||||           ........|.
  Fly   279 SGSRSSP-------AGPHHSAA-----LAAHQHAAAAAAAAHHH-----------AAAAAAAHHA 320

  Fly   232 PHPHLPP-GQIPLGIFPGGPHPGHPP-PHGHHP---------FGSAPHLIRDSYPLYPWLLSRHG 285
            .|.|... ......:.....|..|.. .|.||.         .|..|:.          ||:.||
  Fly   321 HHAHAQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNS----------LLAAHG 375

  Fly   286 RIFPRFPGNFLFQP-------FRKPKR--VRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLS 341
                   |:.|..|       .:|.||  .||.|:.:||.:||.||:..||...:.|:.|:....
  Fly   376 -------GDVLVGPGGTGPGGKKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTG 433

  Fly   342 LTETQVKVWFQNRRTKHKRMQQEGG---------------------------------------- 366
            |.|.:::||:||||.|.::.::..|
  Fly   434 LAEDRIQVWYQNRRAKWRKTEKCWGHSTKMAEYGLYGAMVRHSLPLPETIIKSAKEDESVAPWLL 498

  Fly   367 -------------------------DGSDTKSNKGSS--------------------SGGGGGGD 386
                                     |.::|..:.||:                    :.|..||.
  Fly   499 GMHKKSLEAAELLKSDESDRETPTSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSAGGK 563

  Fly   387 G--EDDAKHDGSQHSYEDAEDPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQH 449
            |  .....|.|..|::..|                         :..|..|..|..|.|||..|.
  Fly   564 GHHHHHHHHKGHHHAHVHA-------------------------QAQAHAHMLLHHQQQQQQQQQ 603

  Fly   450 QQQF------------MQQNAGE-------------AATLSPQQQHQL-LQQHQQHLQ--QQHHQ 486
            |||.            .||.||.             |.:..|...|.. .|||..|||  ||..|
  Fly   604 QQQHHHHLHAAENSLQQQQVAGTGSGSGSGSGSGTGAGSTGPPAHHPYNQQQHLHHLQQLQQQQQ 668

  Fly   487 QQQHFIQQQQQ 497
            |||...|||||
  Fly   669 QQQQQAQQQQQ 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	24/57 (42%)
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	23/56 (41%)