DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E5 and dlx2b

DIOPT Version :9

Sequence 1:	NP_524825.1	Gene:	E5 / 45396	FlyBaseID:	FBgn0008646	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_571372.1	Gene:	dlx2b / 30557	ZFINID:	ZDB-GENE-980526-18	Length:	276	Species:	Danio rerio

Alignment Length:	113	Identity:	41/113 - (36%)
Similarity:	59/113 - (52%)	Gaps:	8/113 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 KPKRV---RTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQ 363
            |||:|   ||.:|..||..|:..|:...|:...||.:||..|.||:||||:||||||:|.|::.:
Zfish   121 KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLWK 185

  Fly   364 EGGDGSDTKSNKGSSSGGG----GGGD-GEDDAKHDGSQHSYEDAEDP 406
            .|...:|.:...|.|....    .|.| ..:..::||...|.:....|
Zfish   186 NGEIPADQQVASGDSPSSSPPPQAGWDFPPNPTQNDGDTVSEQPTGPP 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	26/51 (51%)
dlx2b	NP_571372.1	DLL_N	29..102	CDD:289198
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	97..123		1/1 (100%)
		Homeobox	128..181	CDD:278475	26/52 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..238		9/43 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900