Protein Alignment E5 and Hmx3

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001099772.1
• Gene: Hmx3 / 293537
• RGDID: 1559927
• Length: 356
• Species: Rattus norvegicus
• Alignment Length: 309
• Identity: 75/309 - (24%)
• Similarity: 97/309 - (31%)
• Gaps: 134/309 - (43%)

  Fly   161 LPAPNLALIGNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAAL-AHHHQQQQQQQQQQLPPV 224
            :|.|         .|:|.....|.||.||.|||....:.|.:...| ..||:.         ||.
  Rat     1 MPEP---------GPDASGTASAPPPQPPPQPPAPKESPFSIRNLLNGDHHRP---------PPK 47

  Fly   225 PTGPPHG---------------------------------------------------PHPHL-- 236
            |..||..                                                   |..:|
  Rat    48 PQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLER 112

  Fly   237 -PPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLY--------PWLLS--RHGRIFPR 290
             |....|..:.|.|   ||.|    .|..|...|:|||.|..        |.|.:  .|..:..:
  Rat   113 SPAWWYPYTLTPAG---GHLP----RPEASEKALLRDSSPASGTDRDSPDPLLKADPDHKELDSK 170

  Fly   291 FPGNFLFQ----------------------------------------PFRKP----KRVRTAFS 311
            .|...:.:                                        |.:||    |:.||.||
  Rat   171 SPDEIILEESDSEEGKKEGEAVPGAAGTTVGATAATPGSEDWKAGADSPEKKPACRKKKTRTVFS 235

  Fly   312 PTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKR 360
            .:|:.:||..|:...|:..:||..||..|.|||||||:||||||.|.||
  Rat   236 RSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKR 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	29/55 (53%)
Hmx3	NP_001099772.1	Homeodomain	228..284	CDD:459649	29/55 (53%)