Protein Alignment E5 and Tlx3

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 320
• Identity: 85/320 - (26%)
• Similarity: 115/320 - (35%)
• Gaps: 96/320 - (30%)

  Fly   167 ALIGNRT---------SPNAMAVRMAGPP--HPPSQPPPFLAAQFQ--MAAALAHHHQ------- 211
            :|.|.||         :|.|...|..|.|  .|||...||...:.:  .:|...|.|:
Mouse     4 SLSGPRTLGKVSVRLEAPGAPWPRRNGDPAASPPSPAQPFRPPRMEAPASAQTPHPHEPISFGID 68

  Fly   212 QQQQQQQQQLPPVPTGP-------------PHGPHPHLPPG--------------QIPLGIFPGG 249
            |......|...|.|.||             |...:|.||..              .:.|.:.|.|
Mouse    69 QILNSPDQDSAPAPRGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAG 133

  Fly   250 --------PHPGHPPPHGHHPFGSA-PHLIRDSYPL--------YPWLLSRHGRIFPRFPGNFLF 297
                    |.||..||    |..|| |.:  .|.|.        :||:.|....:..||......
Mouse   134 VIRVPAHRPLPGAVPP----PLPSALPAM--PSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAAL 192

  Fly   298 QPFR---------------KPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQV 347
            .||.               |.|:.||:||..|:.:||..|....|:..|||..||:.|.:|:.||
Mouse   193 TPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQV 257

  Fly   348 KVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAEDPE 407
            |.||||||||.:|...|..:....::::...           ..:||..|.|..|:..|:
Mouse   258 KTWFQNRRTKWRRQTAEEREAERQQASRLML-----------QLQHDAFQKSLNDSIQPD 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	28/55 (51%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	23/88 (26%)
		Homeodomain	214..270	CDD:459649	28/55 (51%)