Protein Alignment E5 and gbx2

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_694496.1
• Gene: gbx2 / 245948
• ZFINID: ZDB-GENE-020509-2
• Length: 342
• Species: Danio rerio
• Alignment Length: 320
• Identity: 79/320 - (24%)
• Similarity: 99/320 - (30%)
• Gaps: 127/320 - (39%)

  Fly   154 TLIRPLPLPAP-NLALIGNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQ 217
            :||...|.|:| :....|   .|..|..|....|.||..|||.|.   |.|
Zfish    26 SLIGGPPQPSPGHFVYTG---YPMFMPYRSVVLPPPPPPPPPTLP---QSA-------------- 70

  Fly   218 QQQLPPVPTGPPHGPHPHLPPG------------QIPLGIFPGG--PHPGHPPPHGHHPFGS-AP 267
                  :||..||.|.|.||..            ...:...|||  ..|...........|| :.
Zfish    71 ------LPTTHPHHPIPGLPSSFCSSLAQGMALTSTLMATLPGGFSSSPSQQHQDAARKLGSQSI 129

  Fly   268 HLIRD-SYPLYPWLLSRHGRIF--------PRF-------------------------------- 291
            |.:.| |..:.  |....|:.|        |.|
Zfish   130 HAMFDKSQDIR--LDGEDGKTFATKDSTSIPSFHDSQSVHTSTVRGHSKDDSKEDDCHRKDESFS 192

  Fly   292 -------------PGNFLFQ------------------------PFRKPKRVRTAFSPTQLLKLE 319
                         |||.:.|                        ...|.:|.||||:..|||:||
Zfish   193 MDSDLDYSSDDNGPGNAMCQKEDGDGSGGLDDGVHGGNGAGNTTSTGKNRRRRTAFTSEQLLELE 257

  Fly   320 HAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSS 379
            ..|....|:...||.|:|..|.|:|.|||:||||||.|.||::     ..:..|..|..|
Zfish   258 KEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVK-----AGNVNSKTGEPS 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	29/55 (53%)
gbx2	NP_694496.1	Homeodomain	242..298	CDD:459649	29/55 (53%)