Protein Alignment E5 and EMX1

DIOPT Version :9

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 109/283 - (38%)
• Similarity: 132/283 - (46%)
• Gaps: 43/283 - (15%)

  Fly   106 RDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIG 170
            |.:|.|:|.|:.:|.:.:...|.|..........||.|....|||.          ......|:.
Human    16 RGALPRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGG----------GGAGSHLLA 70

  Fly   171 NRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPH 235
            ...|...:.......|||.:....|::. |. |||.|...:......:...|.....|....||.
Human    71 AAASEEPLRPTALNYPHPSAAEAAFVSG-FP-AAAAAGAGRSLYGGPELVFPEAMNHPALTVHPA 133

  Fly   236 LPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIF-PRF-------P 292
            ...|..||          .||    |.|..|.|  ||....|||:|  ..|.| .||       .
Human   134 HQLGASPL----------QPP----HSFFGAQH--RDPLHFYPWVL--RNRFFGHRFQASDVPQD 180

  Fly   293 GNFLFQPF-RKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRT 356
            |..|..|| |||||:||||||:|||:||.|||.|||||||||||||..|||:|||||||||||||
Human   181 GLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRT 245

  Fly   357 KHKR--MQQEGGDGSDTKSNKGS 377
            |:||  :::||.:....|  |||
Human   246 KYKRQKLEEEGPESEQKK--KGS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	44/51 (86%)
EMX1	NP_004088.2	COG5576	140..>251	CDD:227863	73/128 (57%)
		Homeobox	196..248	CDD:278475	44/51 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..257		31/40 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6707
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4276
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000921
OrthoInspector	1	1.000	-	-		mtm8552
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24339
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3162
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.950