Protein Alignment E5 and EMX1

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 109/283 - (38%)
• Similarity: 132/283 - (46%)
• Gaps: 43/283 - (15%)

  Fly   106 RDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIG 170
            |.:|.|:|.|:.:|.:.:...|.|..........||.|....|||.          ......|:.
Human    16 RGALPRARLPRTAPAAATMFQPAAKRGFTIESLVAKDGGTGGGTGG----------GGAGSHLLA 70

  Fly   171 NRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPH 235
            ...|...:.......|||.:....|::. |. |||.|...:......:...|.....|....||.
Human    71 AAASEEPLRPTALNYPHPSAAEAAFVSG-FP-AAAAAGAGRSLYGGPELVFPEAMNHPALTVHPA 133

  Fly   236 LPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIF-PRF-------P 292
            ...|..||          .||    |.|..|.|  ||....|||:|  ..|.| .||       .
Human   134 HQLGASPL----------QPP----HSFFGAQH--RDPLHFYPWVL--RNRFFGHRFQASDVPQD 180

  Fly   293 GNFLFQPF-RKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRT 356
            |..|..|| |||||:||||||:|||:||.|||.|||||||||||||..|||:|||||||||||||
Human   181 GLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRT 245

  Fly   357 KHKR--MQQEGGDGSDTKSNKGS 377
            |:||  :::||.:....|  |||
Human   246 KYKRQKLEEEGPESEQKK--KGS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	46/55 (84%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	46/55 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		7/20 (35%)