DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E5 and Msx3

DIOPT Version :9

Sequence 1:	NP_524825.1	Gene:	E5 / 45396	FlyBaseID:	FBgn0008646	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_034966.1	Gene:	Msx3 / 17703	MGIID:	106587	Length:	204	Species:	Mus musculus

Alignment Length:	148	Identity:	57/148 - (38%)
Similarity:	69/148 - (46%)	Gaps:	37/148 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 HGPHPH-----LPPGQIP------LGIFP--GGPHPG-HPPPHGHHPFGSAPHLIRDSYPLYPWL 280
            |||.|.     |...::|      ||:..  |...|| .|||..|.....||     |.|  |..
Mouse    23 HGPLPFSVESLLEAERVPGSESGELGVERPLGASKPGAWPPPVAHSCPPRAP-----SPP--PCT 80

  Fly   281 LSRHGRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTET 345
            |.:|             :..|||   ||.|:..|||.||..|....|:..|||.:.:..||||||
Mouse    81 LRKH-------------KTNRKP---RTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSLTET 129

  Fly   346 QVKVWFQNRRTKHKRMQQ 363
            |||:||||||.|.||:|:
Mouse   130 QVKIWFQNRRAKAKRLQE 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	29/51 (57%)
Msx3	NP_034966.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..89		17/69 (25%)
Msx3	NP_034966.1	Homeobox	90..143	CDD:278475	30/55 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810