Protein Alignment E5 and mab-5

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_498695.1
• Gene: mab-5 / 176091
• WormBaseID: WBGene00003102
• Length: 200
• Species: Caenorhabditis elegans
• Alignment Length: 271
• Identity: 65/271 - (23%)
• Similarity: 91/271 - (33%)
• Gaps: 91/271 - (33%)

  Fly   134 AAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLAL--IGNRTSPNAMAVRMAGPPHPPSQPPPFL 196
            |.||.||.|...||||....:........|.||..  :.|.|..|.|. .|.......:...||.
 Worm    15 AGAGTTASSQSASSGTSASASSSAAAAAAANNLKTYELYNHTYMNNMK-HMLAAGWMDNSSNPFA 78

  Fly   197 AAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGHH 261
            ....|..:|       ...:.:..:|.:
 Worm    79 YNPLQATSA-------NFGETRTSMPAI------------------------------------- 99

  Fly   262 PFGSAPHLIRDSYPLYPWLL---SRHGRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFE 323
                       |.|::||:.   ::.|                :.||.|..:|.:|.|:||..|.
 Worm   100 -----------SQPVFPWMKMGGAKGG----------------ESKRTRQTYSRSQTLELEKEFH 137

  Fly   324 GNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGE 388
            .:.|:....|:::::.|.|||.|||:||||||.|||            |..||  .||....|.|
 Worm   138 YHKYLTRKRRQEISETLHLTERQVKIWFQNRRMKHK------------KEAKG--EGGSNESDEE 188

  Fly   389 DDAKHDGSQHS 399
            .:......|||
 Worm   189 SNQDEQNEQHS 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	26/55 (47%)
mab-5	NP_498695.1	Homeodomain	118..174	CDD:459649	27/67 (40%)