DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E5 and pal-1

DIOPT Version :9

Sequence 1:	NP_524825.1	Gene:	E5 / 45396	FlyBaseID:	FBgn0008646	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001021209.1	Gene:	pal-1 / 175638	WormBaseID:	WBGene00003912	Length:	270	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	70/291 - (24%)
Similarity:	92/291 - (31%)	Gaps:	106/291 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 PQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMA 179
            |.|..:.:....|...|..:..|:|...|.|.         :.|..||    .|..|...|...|
Worm    42 PLREKMLQPTFDPQIYGRWSQMGDTGFYGHPD---------LYPFGLP----QLAANGQIPAVEA 93

  Fly   180 VRMAGP-------------PHPPSQPPPF------------------LAAQFQMAAALAHHHQ-- 211
            |.:..|             |.|.....||                  .||.:||.||..:...
Worm    94 VDVKPPLSNGSSSSDSGMYPSPSDMMTPFPSTSSGAASSSELSAAAAAAANYQMRAATCYQQSVW 158

  Fly   212 --QQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSY 274
              ...||.|.....:|.|..||..                                     |.|
Worm   159 PFMDYQQFQGFSWKMPLGNNHGKD-------------------------------------RRS- 185

  Fly   275 PLYPWLLSRHGRIFPRFPGNFLFQPFRKPKRVRTA------FSPTQLLKLEHAFEGNHYVVGAER 333
                   |..|:..|..||.       ...|||||      :|..|.|:||..|..:.::....:
Worm   186 -------SSDGKTLPTGPGT-------NNVRVRTADKYRMVYSDYQRLELEKEFHTSPFITSDRK 236

  Fly   334 KQLAQGLSLTETQVKVWFQNRRTKHKRMQQE 364
            .||:..|||||.|:|:||||||.|.:|.:|:
Worm   237 SQLSTMLSLTERQIKIWFQNRRAKDRRDKQK 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	25/57 (44%)
pal-1	NP_001021209.1	Homeobox	210..262	CDD:278475	22/51 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000