Protein Alignment E5 and DLX3

DIOPT Version :9

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 57/205 - (27%)
• Similarity: 80/205 - (39%)
• Gaps: 51/205 - (24%)

  Fly   234 PHLPPGQI-PLGIFPGGPH---PGHP------PPHGHHPF------GSAPHLIRDSYPLYPWLLS 282
            |.||...: .||.:....|   .|.|      |...||.|      |:..:..:..|
Human    30 PTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEY-------- 86

  Fly   283 RHGRIFPRFPGNFLFQPF--------------------RKPKRV---RTAFSPTQLLKLEHAFEG 324
            .:|..:.:: |.:..||.                    .|||:|   ||.:|..||..|:..|:.
Human    87 TYGASYRQY-GAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQK 150

  Fly   325 NHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGED 389
            ..|:...||.:||..|.||:||||:||||||:|.|::.:.|....:...|...|.   .......
Human   151 AQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSM---ACNSPPS 212

  Fly   390 DAKHDGSQHS 399
            .|..|.|.||
Human   213 PALWDTSSHS 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	26/51 (51%)
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		3/8 (38%)
		DLL_N	27..107	CDD:403572	18/85 (21%)
		COG5576	<109..232	CDD:227863	39/117 (33%)
		homeobox	129..188		28/58 (48%)
		Homeobox	132..186	CDD:395001	26/53 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810