Protein Alignment E5 and DLX1

DIOPT Version :9

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 66/237 - (27%)
• Similarity: 90/237 - (37%)
• Gaps: 65/237 - (27%)

  Fly   184 GPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPG 248
            |||:....|.|.....:.|....:..|.|                |.|.:........|||.
Human    24 GPPNQQMSPSPMSHGHYSMHCLHSAGHSQ----------------PDGAYSSASSFSRPLGY--- 69

  Fly   249 GPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRH----------------GRIFPRFPGNFLF 297
             |:......|...|:.|:.    .|||....|....                |.:  ||.|.  .
Human    70 -PYVNSVSSHASSPYISSV----QSYPGSASLAQSRLEDPGADSEKSTVVEGGEV--RFNGK--G 125

  Fly   298 QPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQ 362
            :..|||   ||.:|..||..|...|:...|:...||.:||..|.||:||||:||||:|:|.|::.
Human   126 KKIRKP---RTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLM 187

  Fly   363 QEGG---DGSDTKS---------------NKGSSSGGGGGGD 386
            ::||   :||...:               |..||||.|.||:
Human   188 KQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGN 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	25/51 (49%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		1/22 (5%)
		Homeobox	131..185	CDD:395001	26/56 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		8/26 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810