Protein Alignment E5 and Hoxa1

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_034579.3
• Gene: Hoxa1 / 15394
• MGIID: 96170
• Length: 336
• Species: Mus musculus
• Alignment Length: 255
• Identity: 66/255 - (25%)
• Similarity: 87/255 - (34%)
• Gaps: 92/255 - (36%)

  Fly   208 HHHQQQQQQQQQQLPPVPT-------------GPPHGPH----PHLPPGQIPLGIFPGGPHPGHP 255
            |||.........|.....|             ||.:|..    |:.|.|........||..|..|
Mouse    65 HHHHHHHHHHHPQTATYQTSGNLGISYSHSSCGPSYGAQNFSAPYGPYGLNQEADVSGGYPPCAP 129

  Fly   256 P-----------PHGHHPFGSA------PHLIRDSY-----------------PL---------- 276
            .           .|.||..|.|      |..|..||                 ||
Mouse   130 AVYSGNLSTPMVQHHHHHQGYAGGTVGSPQYIHHSYGQEQQTLALATYNNSLSPLHASHQEACRS 194

  Fly   277 -----------YPWLLSRH-----GRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGN 325
                       :.|:..:.     |::     |.:.:  ..:|..|||.|:..||.:||..|..|
Mouse   195 PASETSSPAQTFDWMKVKRNPPKTGKV-----GEYGY--VGQPNAVRTNFTTKQLTELEKEFHFN 252

  Fly   326 HYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEG--------GDGSDTKSNKGS 377
            .|:..|.|.::|..|.|.|||||:||||||.|.|:.::||        ..|||.|:.:.|
Mouse   253 KYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGSDEKTEESS 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	28/55 (51%)
Hoxa1	NP_034579.3	COG5576	177..>287	CDD:227863	34/116 (29%)
		Homeodomain	234..287	CDD:459649	27/52 (52%)