Protein Alignment E5 and Emx2

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_034262.2
• Gene: Emx2 / 13797
• MGIID: 95388
• Length: 253
• Species: Mus musculus
• Alignment Length: 343
• Identity: 118/343 - (34%)
• Similarity: 143/343 - (41%)
• Gaps: 132/343 - (38%)

  Fly    48 PKLAFSIDSIVGESSTRSAPLRVSVISSPPPRSESPASPTNTNNSGRRTPRGYIYCRRRDSLDRS 112
            ||..|:|:|:|.:.|    ||       |..|||.|..|.                    :|..:
Mouse     6 PKRCFTIESLVAKDS----PL-------PASRSEDPIRPA--------------------ALSYA 39

  Fly   113 RSPQRSPVSRSPSPPNAGGNPAAAGNTAKSGDPSSGTG---NPPTLIRPLPLPAPNLALIGNRTS 174
            .|   ||:           ||...|..:.:...::|.|   ||..:........||.|:
Mouse    40 NS---SPI-----------NPFLNGFHSAAAAAAAGRGVYSNPDLVFAEAVSHPPNPAV------ 84

  Fly   175 PNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPG 239
                      |.||  .|||.         |||.|             |:|:.  |.|||.....
Mouse    85 ----------PVHP--VPPPH---------ALAAH-------------PLPSS--HSPHPLFASQ 113

  Fly   240 QIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIFPRFPGN------FLFQ 298
            |                              ||....||||:.|:..:..||.||      ||..
Mouse   114 Q------------------------------RDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLH 148

  Fly   299 P--FRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKR- 360
            .  .|||||:||||||:|||:||||||.|||||||||||||..||||||||||||||||||.||
Mouse   149 NALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQ 213

  Fly   361 -MQQEGGDGSDTKSNKGS 377
             :::||.|....|  ||:
Mouse   214 KLEEEGSDSQQKK--KGT 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	48/55 (87%)
Emx2	NP_034262.2	Homeodomain	156..212	CDD:459649	48/55 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	213..253		6/19 (32%)