Protein Alignment E5 and Dlx2

DIOPT Version :9

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_034184.1
• Gene: Dlx2 / 13392
• MGIID: 94902
• Length: 332
• Species: Mus musculus
• Alignment Length: 383
• Identity: 87/383 - (22%)
• Similarity: 114/383 - (29%)
• Gaps: 177/383 - (46%)

  Fly   201 QMAAALAHHHQQQQQQQQQQLPPVPTGPPHGP------------------HPHLPPG-------- 239
            |:.|:..:|..||.          |:|...||                  .|.||..
Mouse    16 QITASSTYHQHQQP----------PSGAGAGPGGNSNSSSSNSSLHKPQESPTLPVSTATDSSYY 70

  Fly   240 ---QIPLGIFPGGPHP-GHPPPHGHH---------------------------PFGSAPHLIR-- 271
               |.|.|...||..| .|...:.:|                           |:|::...:.
Mouse    71 TNQQHPAGGGGGGASPYAHMGSYQYHASGLNNVSYSAKSSYDLGYTAAYTSYAPYGTSSSPVNNE 135

  Fly   272 -DSYPLYPWLLSRHGRIFPRFPGNFLFQPFRKPKRV---RTAFSPTQLLKLEHAFEGNHYVVGAE 332
             |...|.|.:...:|                |||:|   ||.:|..||..|:..|:...|:...|
Mouse   136 PDKEDLEPEIRIVNG----------------KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPE 184

  Fly   333 RKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSS------------------ 379
            |.:||..|.||:||||:||||||:|.|:|.:.|  ...|:.:.|:|:
Mouse   185 RAELAASLGLTQTQVKIWFQNRRSKFKKMWKSG--EIPTEQHPGASASPPCASPPVSAPASWDFG 247

  Fly   380 -----GGGGGGDGEDDAKHDGSQHS------------YEDAEDPEDEDEIEEDDEDEVIDMDDYG 427
                 .|||.|.|...|...||..|            |..|.                      |
Mouse   248 APQRMAGGGPGSGGGGAGSSGSSPSSAASAFLGNYPWYHQAS----------------------G 290

  Fly   428 SEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQHQLLQQHQQHLQQQHH 485
            |                  |.|.|       ..|..|.|.|..|....|..|    ||
Mouse   291 S------------------ASHLQ-------ATAPLLHPSQTPQAHHHHHHH----HH 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeobox	307..359	CDD:278475	26/51 (51%)
Dlx2	NP_034184.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..83		14/73 (19%)
		DLL_N	54..135	CDD:289198	13/80 (16%)
		Homeobox	158..211	CDD:278475	26/52 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..272		11/52 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..332		7/20 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810