DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment E5 and Msx3

DIOPT Version :9

Sequence 1:NP_524825.1 Gene:E5 / 45396 FlyBaseID:FBgn0008646 Length:524 Species:Drosophila melanogaster
Sequence 2:NP_446164.1 Gene:Msx3 / 114504 RGDID:620932 Length:204 Species:Rattus norvegicus


Alignment Length:151 Identity:53/151 - (35%)
Similarity:65/151 - (43%) Gaps:45/151 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   235 HLPPGQIPLGIF---------------------PGGPHPG-HPPPHGHHPFGSAPHLIRDSYPLY 277
            |:..|.:|..:.                     ||...|| .|||..|.....||     |.|  
  Rat    20 HIEQGPLPFSVESLLEAERVRGSESGELGEERPPGASKPGAWPPPVAHSCPPRAP-----SPP-- 77

  Fly   278 PWLLSRHGRIFPRFPGNFLFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSL 342
            |..|.:|             :..|||   ||.|:..|||.||..|....|:..|||.:.:..|||
  Rat    78 PCTLRKH-------------KTNRKP---RTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSL 126

  Fly   343 TETQVKVWFQNRRTKHKRMQQ 363
            ||||||:||||||.|.||:|:
  Rat   127 TETQVKIWFQNRRAKAKRLQE 147

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E5NP_524825.1 Homeobox 307..359 CDD:278475 29/51 (57%)
Msx3NP_446164.1 Homeobox 90..144 CDD:395001 30/56 (54%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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