Protein Alignment E5 and LOC11175693

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_061504020.1
• Gene: LOC11175693 / 11175693
• VectorBaseID: AGAMI1_013927
• Length: 667
• Species: Anopheles gambiae
• Alignment Length: 541
• Identity: 126/541 - (23%)
• Similarity: 167/541 - (30%)
• Gaps: 231/541 - (42%)

  Fly    17 TSPFVSSSSSVAA----SSTSVSASSTVSASASSKPKLAFSIDSIVG---ESSTRSAPLRVSVIS 74
            |..||..|.::||    ......|::..:|.||...:.|.::.:..|   :....:|.:..:.:.
Mosquito   258 TDGFVGKSFTIAAILGLRKQQDEAAAAAAAVASEYSEGAMNLSTGAGFQQQQRVAAAAVAAAAMG 322

  Fly    75 SPPPRSESPASPTNTNNSGRRTPRGYIYCRRRDSLDR------------SRSPQRSPVSRSPSP- 126
            ..|....:.|......:             |.||:|.            .:..|:.|...|.|.
Mosquito   323 RLPLVMAAAAVGMEKRD-------------RADSVDSVDTCGGSLGYGPQQQQQQQPAGGSLSAL 374

  Fly   127 ------PNAGGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAMAVRMAGP 185
                  |...|   |.|.:..:..||.|:|                         :|.|.:....
Mosquito   375 QNLHQLPGLHG---AVGGSFSAFHPSGGSG-------------------------SASAHQQQHL 411

  Fly   186 PHPPSQPP--------------PFLAAQFQMAAALA----HHH--QQQQQQQQQQLPPVPTGPPH 230
            .||....|              |..|...|::...|    |||  ||||||||||........|.
Mosquito   412 HHPHQHHPHHHHPHQHHHQHHHPHHALHHQVSPHFAGNPFHHHQGQQQQQQQQQQSQQQMQQQPS 476

  Fly   231 GPHPHLPPGQIPLGIFPGGPHPGHPPPH------GHHPFGSAPHLIRDSYPLYPWLLSRHGRIFP 289
            ..|.|||.               |...|      ||| ....||              .||:
Mosquito   477 QQHQHLPQ---------------HAVAHQQQLAAGHH-MALGPH--------------HHGQ--- 508

  Fly   290 RFPGNFLFQPFR---------------KPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQG 339
                |...:.|:               |.|||||.|:|.||.:||..||...|:||.||..||..
Mosquito   509 ----NHNREKFKDLSKKSAMSSSAASLKSKRVRTIFTPEQLERLEAEFERQQYMVGPERLYLAHT 569

  Fly   340 LSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSYEDAE 404
            |.|||.||||||||||.|.::                                     |..|..:
Mosquito   570 LQLTEAQVKVWFQNRRIKWRK-------------------------------------HHLEITQ 597

  Fly   405 DPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLSPQQQ 469
                                           |||....|:|:|..    :...|||
Mosquito   598 -------------------------------QRLALIRQRQIANG----VPIPAGE--------- 618

  Fly   470 HQLLQQHQQHLQQQHHQQQQH 490
               :|.|  |:|||..||||:
Mosquito   619 ---VQPH--HIQQQQQQQQQN 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	35/55 (64%)
LOC11175693	XP_061504020.1	None