Protein Alignment E5 and hoxd3

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_002935734.1
• Gene: hoxd3 / 100038058
• XenbaseID: XB-GENE-478462
• Length: 415
• Species: Xenopus tropicalis
• Alignment Length: 376
• Identity: 90/376 - (23%)
• Similarity: 134/376 - (35%)
• Gaps: 114/376 - (30%)

  Fly   150 GNPPTLIRPLPLPA----PNLALIGNRT--SPNAMAVRMAGPPHPPS---QPPPFLAAQFQMAAA 205
            |:.|..||...:..    .|..|.|..|  .|.:.:...:...:|.|   ...|..|...|.||.
 Frog     6 GSNPLSIREAKMQKTAYYENSGLFGGYTYAKPESYSYGPSQQQYPQSSLDSDYPSTACSIQPAAI 70

  Fly   206 LAHHHQQQ----------QQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGH 260
            .|.:|:..          ..|...|.|.: :...| ..|.|||..               |.||:
 Frog    71 RAPNHKANDISGSCMRTTSSQNSNQAPSI-SNQQH-QAPSLPPSS---------------PSHGN 118

  Fly   261 ----------HPFGSAPHLIRDSYPLYPWLLSRHGRIFPRFPGNFLFQP------FRKP-----K 304
                      :..||:...:  |..::||:.........:...:....|      .:.|     |
 Frog   119 SSAQKKSKSSNSSGSSQATL--SKQIFPWMKESRQNAKQKNTSSSSSTPPGENCEEKSPTGPSSK 181

  Fly   305 RVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGG--- 366
            |||||::..||::||..|..|.|:....|.::|..|:|||.|:|:||||||.|:|:.|:..|
 Frog   182 RVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGIMH 246

  Fly   367 -------DGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQH-------------SYEDAEDPEDEDE 411
                   |.|.|.|                     ||.|             || ||..|....:
 Frog   247 SPAGQSPDRSPTLS---------------------GSNHVGYSSQLPTVNSLSY-DAPSPTSFAK 289

  Fly   412 IEEDDEDEVIDMDDYG-SEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEA 461
            .::         :.|| :...|.....|.:|.:...|:::...||.|:|.|
 Frog   290 SQQ---------NMYGLAAYTAPLSSCLPQQKRYPGAEYEHHTMQGNSGFA 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	28/55 (51%)
hoxd3	XP_002935734.1	Homeodomain	181..237	CDD:459649	28/55 (51%)
		DUF4074	352..413	CDD:463833