Protein Alignment E5 and tlx3a

DIOPT Version :10

• Sequence 1: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_003199819.1
• Gene: tlx3a / 100008066
• ZFINID: ZDB-GENE-080724-11
• Length: 251
• Species: Danio rerio
• Alignment Length: 276
• Identity: 68/276 - (24%)
• Similarity: 97/276 - (35%)
• Gaps: 107/276 - (38%)

  Fly   234 PHLP-PG----------QIPLGIFPGG--PHPGHPPPHGHHPFGSAPHLIRDSYPL-YPWLLSRH 284
            ||:| ||          .:...:.|||  ..|.|.|        .||.::..:..| :||:  .:
Zfish    42 PHVPLPGVSLEESGRVFGVSSALLPGGVIRVPAHRP--------LAPAMMSAAPALCFPWM--DN 96

  Fly   285 GRIFP--RFPGNFLF-------QPFR-----KPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQ 335
            .|.||  |.|....|       .|::     |.|:.||:||..|:.:||..|....|:..|||..
Zfish    97 NRRFPKDRLPALIPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAA 161

  Fly   336 LAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSSSGGGGGGDGEDDAKHDGSQHSY 400
            ||:.|.:|:.|||.||||||||.:|
Zfish   162 LAKSLKMTDAQVKTWFQNRRTKWRR---------------------------------------- 186

  Fly   401 EDAEDPEDEDEIEEDDEDEVIDMDDYGSEMDAEEHQRLREQFQQQLAQHQQQFMQQNAGEAATLS 465
                                         ..|||.:..|:|..:.|.|.|...:|::..|:.:..
Zfish   187 -----------------------------QTAEEREAGRQQANRMLLQLQADALQKSISESVSSD 222

  Fly   466 PQQQHQLLQQHQQHLQ 481
            |...|.......|:||
Zfish   223 PLCLHNSSLYALQNLQ 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	28/55 (51%)
tlx3a	XP_003199819.1	Homeodomain	130..186	CDD:459649	28/55 (51%)