DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ogre and Inx3

DIOPT Version :9

Sequence 1:NP_001245557.1 Gene:ogre / 45382 FlyBaseID:FBgn0004646 Length:362 Species:Drosophila melanogaster
Sequence 2:NP_001263050.1 Gene:Inx3 / 44266 FlyBaseID:FBgn0265274 Length:395 Species:Drosophila melanogaster


Alignment Length:331 Identity:146/331 - (44%)
Similarity:221/331 - (66%) Gaps:4/331 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 DNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIVNG-VPPHVVNTFCWIHSTFTMPDAFRRQ 83
            ||.|||.|...||.:|.||.:|:||...:|.|||||.:| :|.||:||||||..|:|:|....||
  Fly    26 DNMVFRCHYRITTAILFTCCIIVTANNLIGDPISCINDGAIPMHVINTFCWITYTYTIPGQQHRQ 90

  Fly    84 VGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGLMRMIVMGLNIT 148
            :|.:||.||:.|::|.|  |:|::|||||.||||||.:..|.|.::|...|.|.:|||..||...
  Fly    91 IGTDVAGPGLGNEYGQE--KRYHSYYQWVPFVLFFQGLMFYVPHWVWKNMEDGKIRMITDGLRGM 153

  Fly   149 ICTREE-KEAKRDALLDYLIKHVKRHKLYAIRYWACEFLCCINIIVQMYLMNRFFDGEFLSYGTN 212
            :...:: :..::|.:|.|.:..:..|..|:..|:.||.|..||:||.::::::|..|.|:||||:
  Fly   154 VSVPDDYRRDRQDRILKYFVNSLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFLGGAFMSYGTD 218

  Fly   213 IMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEKTYVFIWFWFWI 277
            ::|.|::.|::|.|||:.:|||:|||||||:|||||:||||:||:|.|||:|||.|:|:||||.|
  Fly   219 VLKFSNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFII 283

  Fly   278 LLVLLIGLIVFRGCIIFMPKFRPRLLNASNRMIPMEICRSLSRKLDIGDWWLIYMLGRNLDPVIY 342
            |..:....:::...:|.||..|..::..|.|....:....|.|:|:|||:.:::.|.:||....|
  Fly   284 LATISGVAVLYSLVVIMMPTTRETIIKRSYRSAQRKEIAGLVRRLEIGDFLILHFLSQNLSTRSY 348

  Fly   343 KDVMSE 348
            .|::.:
  Fly   349 SDMLQQ 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ogreNP_001245557.1 Innexin 20..351 CDD:279248 146/331 (44%)
Inx3NP_001263050.1 Innexin 26..356 CDD:279248 146/331 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 133 1.000 Domainoid score I3133
eggNOG 1 0.900 - - E1_2BWHM
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 134 1.000 Inparanoid score I3152
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D323554at33208
OrthoFinder 1 1.000 - - FOG0003274
OrthoInspector 1 1.000 - - mtm4755
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR11893
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X282
98.970

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