Protein Alignment fwd and PI-4KBETA2

DIOPT Version :10

• Sequence 1: NP_001356971.1
• Gene: fwd / 45374
• FlyBaseID: FBgn0004373
• Length: 1682
• Species: Drosophila melanogaster
• Sequence 2: NP_196497.1
• Gene: PI-4KBETA2 / 830794
• AraportID: AT5G09350
• Length: 1116
• Species: Arabidopsis thaliana
• Alignment Length: 1177
• Identity: 290/1177 - (24%)
• Similarity: 438/1177 - (37%)
• Gaps: 429/1177 - (36%)

  Fly   857 ALTKCSSINSIHKLKLPVPGVVKYFISEKAPVSDVLQKPEKGQSG-LLRFFESPVFNIHFAVHYL 920
            :|.:..||.|..::..|               |:::.  |.|.:| |:|||:|..|....||.||
plant     8 SLVRGDSIESPREITSP---------------SNLIS--ESGSNGWLIRFFDSSFFCEWIAVSYL 55

  Fly   921 FYSKEPGVLSFIGNKIFSFPDQEVDLYIPQLVVMYIQMDELAEVLDPYLTIRCRKSVDFSLKCLW 985
            :..:..||..::.|::::.|...::.|:.|  :.|:.:.:.:..||.::...|.||:..:||..|
plant    56 YKHQHSGVRDYLCNRMYTLPLSGIESYLFQ--ICYLMVHKPSPSLDKFVIDICAKSLKIALKVHW 118

  Fly   986 LLEAYNYQVDS-----------------------LGNSHNS-------------SRKSKL----- 1009
            .|.|.....|.                       |...||.             |.|.||
plant   119 FLLAELEDSDDNEGISRIQEKCQIAATLVGEWSPLMRPHNEPSTPGSKVLNKFLSSKQKLFSLTL 183

  Fly  1010 --------------------------------------------ALM-------------KEIFS 1017
                                                        ||:             |:.|.
plant   184 SPPTQKSLLFSPTSGSNLQDDGSQLSADDNKIFKRLIPSPKVRDALLFRKSADKEDEECEKDGFF 248

  Fly  1018 KR-----------------------------EHKQTQN-----------------DLKSAGTGGL 1036
            ||                             |.::..|                 :|.|:..|..
plant   249 KRLLRDSRGEDDEQRSNSEGFFKRLLKDNKSEEEEISNNSEGFFKRLRSSKGDEEELTSSSDGFF 313

  Fly  1037 ------------HVG-------------------EPR-SVVALAKKTHH---------------- 1053
                        .:|                   ||. :.....||..|
plant   314 KRLLRDNKGDEEELGANSEGFFKKLLRDSKNEDEEPNANTEGFFKKLFHESKNEDDKVSNAVDDE 378

  Fly  1054 ----------------------RSQSDATVLLAD---------------FR-----SPH------ 1070
                                  |:::|.||...:               |:     .|:
plant   379 EKDGFLKKLFKEKFDEKRNGNERNETDETVYTDETSGEDNGREGFFKKLFKEKFEDKPNIGKADD 443

  Fly  1071 ----------TLSISHRMYQQPPYTTQTLPTTPAKLCL--GDLTSGHAFDNGCTCFETV------ 1117
                      ..|:..|::::.|...:|  |.|::.|.  |.:.|....:|   .|..:
plant   444 GNESEDDESSEFSLFRRLFRRHPEDVKT--TLPSENCSNGGFVESSPGTEN---FFRKLFRDRDR 503

  Fly  1118 ---RGQVNGLLGQRTLCSCGAPK---TSPQK---------------------EFMKALMNVGKNL 1155
               ..::.|....:..|. |:||   .:|.|                     ||:.||.....:|
plant   504 SVEDSELFGSKKYKEKCP-GSPKPQNNTPSKKPPLPNNTAAQFRKGSYHESLEFVHALCETSYDL 567

  Fly  1156 TS-WPSKAEKTSALRMSLNLINKNL-----PARVWLPLYSDIPHHVVRITEEKTAVLNSKDKTPY 1214
            .. :|.:..|| |||.|:..||.:|     ...:..|:...: :.||.|.|::..:|||::|.||
plant   568 VDIFPIEDRKT-ALRESIAEINSHLAQAETTGGICFPMGRGV-YRVVNIPEDEYVLLNSREKVPY 630

  Fly  1215 IIYVEVVEI-------------------------------PDIYTSPL----------------- 1231
            :|.|||::.                               |..:..||
plant   631 MICVEVLKAETPCGAKTTSTSLKLSKGGIPLANGDAFLHKPPPWAYPLSTAQEVYRNSADRMSLS 695

  Fly  1232 -IPKMMPSLRHTKSEEHLDGSCLNSHQHLSCSRTSSCSSSQQGTSCRRKKGADVD----GGCGDA 1291
             :..:..::.| |||..|..:||:...| |.|.|.|.||...|.   .:.|.:.|    .....|
plant   696 TVEAIDQAMTH-KSEVKLVNACLSVETH-SNSNTKSVSSGVTGV---LRTGLESDLEWVRLVLTA 755

  Fly  1292 GPHNSCSNVHSLGGLQFQEDDVWSQEEDEITAQYLNMRKVSERDTISQISLDSCDSRDQGPPVVF 1356
            .|           ||:.:      ...|..|.:....|:||  ..::...:.:..::.:.||
plant   756 DP-----------GLRME------SITDPKTPRRKEHRRVS--SIVAYEEVRAAAAKGEAPP--- 798

  Fly  1357 NIGDVRLRHCSNLSCENTKSFSNDPEDPSA---------AALKEPWHEKEKLIRESSPYGHLSNW 1412
                       .|..:.....|:|.: |.|         |...|.|..|...||:.|.||:|..|
plant   799 -----------GLPLKGAGQDSSDAQ-PMANGGMLKAGDALSGEFWEGKRLRIRKDSIYGNLPGW 851

  Fly  1413 RLLSAIVKCGDDLRQELMATQLLQMFKIIWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTVSLHQ 1477
            .|.|.|||.|||.|||.:|.||:..|..|:||..:.||:|||:::..|:.:.|||.|.:|.|:|.
plant   852 DLRSIIVKSGDDCRQEHLAVQLISHFFDIFQEAGLPLWLRPYEVLVTSSYTALIETIPDTASIHS 916

  Fly  1478 IKKN--SNKSLKEYFIDEYGSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDRHNGNILFHSDGH 1540
            ||..  :..||:::| |.....:..||:.||:|||:|.|.|.|:.||||:|||||||:|...:||
plant   917 IKSRYPNITSLRDFF-DAKFKENSPSFKLAQRNFVESMAGYSLVCYLLQIKDRHNGNLLMDEEGH 980

  Fly  1541 IIHIDFGFILSISPKNLGFEQSPFKLTPEFVEVMG----GTSSEHWREFNKLLLVGMMSARKHMD 1601
            ||||||||:||.||..:.||.:|||||.|.:|||.    |..||.:..|..|.:.|.::.|||.:
plant   981 IIHIDFGFMLSNSPGGVNFESAPFKLTRELLEVMDSDAEGLPSEFFDYFKVLCIQGFLTCRKHAE 1045

  Fly  1602 RIINFVEIMRSNAHLPCFKNGCSGTVQNLRKRFHMNLTEQEMERKVEQLVQDSLKSLSTKLYDGY 1666
            |||..||:::.:. .||||.| ..|:||||||||::|||::....|..|:..||.:..|:.||.|
plant  1046 RIILLVEMLQDSG-FPCFKGG-PRTIQNLRKRFHLSLTEEQCVSLVLSLISSSLDAWRTRQYDYY 1108

  Fly  1667 QYYTNGI 1673
            |...|||
plant  1109 QRVLNGI 1115

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fwd	NP_001356971.1	PI4Kc_III_beta	1385..1674	CDD:270712	140/304 (46%)
PI-4KBETA2	NP_196497.1	BMS1	<240..>405	CDD:227519	16/164 (10%)
		PI4Kc_III_beta	826..1115	CDD:270712	137/291 (47%)