Protein Alignment fwd and pi4kab

DIOPT Version :9

• Sequence 1: NP_001356971.1
• Gene: fwd / 45374
• FlyBaseID: FBgn0004373
• Length: 1682
• Species: Drosophila melanogaster
• Sequence 2: NP_001106813.1
• Gene: pi4kab / 793349
• ZFINID: ZDB-GENE-080220-34
• Length: 1099
• Species: Danio rerio
• Alignment Length: 1349
• Identity: 251/1349 - (18%)
• Similarity: 420/1349 - (31%)
• Gaps: 450/1349 - (33%)

  Fly    52 NKLLS-----PVVVVAEERPVSKAGSPSTVATMATGVDVVDHCLPTTV----------RLSVTEA 101
            |.|||     |.|...||....|......:|      :....||.|.:          |..:.||
Zfish    40 NYLLSLLKGLPRVQWVEENAGRKCKESLPMA------ENFSFCLVTLLSDVAQKDPESRTQILEA 98

  Fly   102 LSDLNMNGKAV-EPP-----------VTPC-----TSVGDNANLEVAETWAC-------PPPQ-- 140
            :.|:..:...: :.|           |.||     .:.|..:|.:  |...|       |||.
Zfish    99 IMDVMQSLLEICQTPENHDKVHLCRFVVPCLLGVARAFGRYSNAD--EPLLCQLFPRGAPPPATP 161

  Fly   141 ---ATDDEDISEHSTAACTSTSSSSEHSNSTVVHSPTV-GESTCDSVSVSVS----HPSPSVSQN 197
               :.:.|.|...|.....|...|   |..||..|.|: .:||..::....|    .|||.
Zfish   162 VRGSVETEGIRRRSFNDFRSILPS---SLLTVCQSDTLRRKSTATNLDAQASPDRGGPSPC---- 219

  Fly   198 NTSSATGRMSSPHSQSSLSIACEPHSASTTTLSSLGSDLGNGNGSTVPAFLMAAPVTLPIGGQMP 262
             :.:|.|......|..|...|..|....||..||.         |..|.|
Zfish   220 -SPTAPGPQYFEGSYLSEGSAVNPDYYFTTVSSSF---------SMSPLF--------------- 259

  Fly   263 TIKCLPGASSAASTPKHSRYSKPRLSLSRV-----------FNHSMPSVHGRPNLSLAPAGVP-- 314
                     |.||.|:   .:.|...|.|:           |..|:.:|  ...::.|.|||.
Zfish   260 ---------SGASGPE---INVPLELLRRLLQMVKQFVSDSFLKSLDAV--VTEVTEANAGVDLF 310

  Fly   315 -GSVNPPKRISTHQRNLSLDFRSMGILLPPVSQVTNNHINHTQH---HRNRSLDSALQRIPEVEV 375
             ...:.|..:|.        |:.:...|..:..|....:.....   .:..|..|.|||:.. |.
Zfish   311 YKGFSDPLYVSM--------FKMLRDTLYYMKDVHAGFVKEVHDFVLEQFSSSQSELQRVLH-EE 366

  Fly   376 SSPNAES-------ENTFCSPSILGA--------TMCSKI-----ATTAATVTSALSPPGTPTPA 420
            ..|...|       .|..|...::.|        .:|:|:     :.|::.|..|..|
Zfish   367 RLPGEASPLKLRCHANAACVDLMVWAVKDEQGAENLCTKLSEKLQSKTSSKVIIAHMP------- 424

  Fly   421 LMSTACTPTIGAVKGNVQHPVPKHEQSISLAAACRSSAVVESCPTLRMRPKSSESVAANGQEMIG 485
             :...|...:|.:  ..:.||..|..|:||    :...||.|...:::....|:..:..|    |
Zfish   425 -LLICCLQGLGRL--CERFPVIAHSASLSL----KDFLVVPSAVLIKLYKYHSQCSSGAG----G 478

  Fly   486 VIVSSTGNGSSSSNNSCSSAGSTKKREDLTSLGSDDSGIICGSESDQISLNRICH---------- 540
            :.::.|...|.||.|..||      |:|..|:         ..:...||::.||.
Zfish   479 IKINVTNEHSQSSLNLLSS------RKDQPSM---------YEQLRDISIDNICRCLKAGLTMDP 528

  Fly   541 ----------SHESLDSGEMDADADAEEE---------CVDLMDTTSIDEEYNIMQPDHLCLYPP 586
                      |:....|.|.|.:|....:         .|.:.|:..:.|....:.....| .||
Zfish   529 VIVEAFLASLSNRLYISQENDKEAHLIPDHTIRALGHIAVAMRDSPKVMEPILQILQQKFC-QPP 592

  Fly   587 QAAST----ELDCRTLRPSRKQKRQQQQVLERKNLPSQNQIES--EDSVDAGVDARTRYRVMNMS 645
            .....    :|.|..:..::...::...:.::.::.:.|.:.|  :|..|.|      ||  :.|
Zfish   593 SPLDVLIIDQLGCMIITGNQYIYQEVWNLFQQISVKASNVVYSATKDYKDHG------YR--HCS 649

  Fly   646 QAAINVELGTASN-EIDPDVN---------------------YRESHQDPIADAPSLSTPSVAST 688
            .|.||.....|:| :.:|.|:                     .|.|.:.|...|.|    |..:.
Zfish   650 LAVINALANIAANLQGEPLVDELLVNLLELFVQLGLEGKRACERASDKGPALKASS----SAGNL 710

  Fly   689 ASATPSVTPTPIATPTPTESTKNDQVLFKNFFGATKNAIFRTAQSIIENHEKKNAAKQKEQPDHS 753
            ....|.:.......|...|:....|.||::|:          ..|::
Zfish   711 GVLIPVIAVLTRRLPPIKEAKPRLQKLFRDFW----------LYSVV------------------ 747

  Fly   754 GTVSLVGSPNGGSSV-PQDLVKSPTDISKKKEFFSLLTSSSSIKAAAAAAANSAASTPPATPTEA 817
                 :|....||.: |::..:...:|:.|.   .|||..|.....:....|||......||.|
Zfish   748 -----MGFAVEGSGLWPEEWYEGVCEIATKS---PLLTFPSGEPLRSELQYNSALKNDTVTPAE- 803

  Fly   818 LAANSNSKLQPLSDPSADLKVKERTLNLRLPGDSEGSEGALTKCSSINSIHKLKLPVPGVVKYFI 882
             .::..|.:..|.|||.:.......|:..:             |:.:.|:::|:     .::...
Zfish   804 -LSDLRSTIINLLDPSPEAAALINKLDFAM-------------CTYLLSVYRLE-----YMRMLH 849

  Fly   883 SEKAPVSDVLQKPEKGQSGLLRFFESPVFNIHFAVHYLFYSKEPGVLS---FIGNKIFSFPDQEV 944
            |..|....|          :.|:||.....          ..:.|::.   .:|:|:|     ||
Zfish   850 SNDADRFQV----------MFRYFEDKAIQ----------KDKSGMMQCVICVGDKVF-----EV 889

  Fly   945 DLYIPQLVVMYIQMDELAEVLDPYLTIRCRKSVDFSLKCLWLLEAYNYQVDSLGNSHNSSRKSKL 1009
            .|   |::....:..|..|.|:.:              ..:||..:|         |...|..::
Zfish   890 FL---QMMAEKPKTKEHEEELERH--------------AQFLLVNFN---------HTHKRIRRV 928

  Fly  1010 ALMKEIFSKREHKQTQNDLKSAGTGGLHVGEPRSVVALAKKTHHRSQSDATV-LLADFRSPHTLS 1073
            |                              .:.:..||:...|...|...: .:.|.....:||
Zfish   929 A------------------------------DKYLSGLAETFPHLLWSGRVLKTMLDILQTLSLS 963

  Fly  1074 ISHRMYQQPPYTTQTLPTTPAKLCLGDLTSGH---AFDNGCTCFETVRGQVNGLLGQRTLCSCGA 1135
            :|..:::..||  ..:|.||.::.:.|.....   ..|....|.|.::..:..
Zfish   964 LSADIHKDQPY--YDIPDTPYRITVPDTHEARESIVKDFAARCGEILKEAMKW------------ 1014

  Fly  1136 PKTSPQKEFMKALMNVGKNLTSWPSKAEKTSALRMS----LNLINKNLPARVWLPLYSDIPHHVV 1196
             ..|..|..::..:|..:|   |.|...:.:.|.|:    ||....|..:.....:.|:
Zfish  1015 -AASVTKSHLQEYLNKHQN---WLSGLSQHTGLAMATESILNFAGYNRQSTTLGMMVSE------ 1069

  Fly  1197 RITEEKTAVLNSKDKTPYIIYVEVVEIPDIYTSPLIPKMMPSLRHTKSE 1245
            |:||               ::|::    .:..|.||.      |||..|
Zfish  1070 RVTE---------------VFVQM----KVSCSSLIS------RHTVGE 1093

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fwd	NP_001356971.1	PI4Kc_III_beta	1385..1674	CDD:270712
pi4kab	NP_001106813.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1147978at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910