DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fwd and Atr

DIOPT Version :9

Sequence 1:	NP_001356971.1	Gene:	fwd / 45374	FlyBaseID:	FBgn0004373	Length:	1682	Species:	Drosophila melanogaster
Sequence 2:	XP_003750609.1	Gene:	Atr / 685055	RGDID:	1305796	Length:	2636	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	72/338 - (21%)
Similarity:	140/338 - (41%)	Gaps:	89/338 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1410 SNWRLLSAIVKCGDDLRQELMATQLLQMFKII-------WQEEQVDLWVRPYKIVCLSNDSGLIE 1467
            |:.:....:.|..||||::   .:|::...:|       .:..:.:|.:|.|.::.|:::.|:||
  Rat  2309 SDGKFYIMMCKPKDDLRKD---CRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIE 2370

  Fly  1468 PILNTVSLHQIKKN---------SNKSLK------------------------------EYFIDE 1493
            .:.||..|..|...         :.|.|:                              |:|:..
  Rat  2371 WVNNTAGLRPILTKLYKEKGVYMTGKELRQCMLPKSAALSEKLKVFQEILLPRHPPVFHEWFLRT 2435

  Fly  1494 YGSPSGESFRRAQKNFVQSCAAYCLISYLLQVKDRHNGNILFHS-DGHIIHIDFGFILSISPKNL 1557
            :..|:  |:..::..:.:|.|...::.|:|.:.|||..||||.| .|..:|:||..:.:   |..
  Rat  2436 FPDPT--SWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFN---KGE 2495

  Fly  1558 GFEQS---PFKLTPEFVEVMGGTSSEH-WREFNKLLLVGMMSARKHM---------DRIINFVEI 1609
            .||..   ||:||...|..||...:|. :|...::.|..|...|:.:         |.::.:.:.
  Rat  2496 TFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKP 2560

  Fly  1610 MRSNAHLPCFKNGCSGTVQNLRKRFHMNLTEQEM-----------------ERKVEQLVQDSL-K 1656
            ::.::..|..:   :|.|.|.:.:.|:...||.:                 |..|..|:|::. :
  Rat  2561 VKGHSKAPPNE---TGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDE 2622

  Fly  1657 SLSTKLYDGYQYY 1669
            :|..::|.|:..|
  Rat  2623 NLLCQMYLGWTPY 2635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fwd	NP_001356971.1	PI4Kc_III_beta	1385..1674	CDD:270712	72/338 (21%)
Atr	XP_003750609.1	UME	1120..1226	CDD:214825
		FAT	1766..2087	CDD:280429
		TEL1	<2118..2636	CDD:227365	72/338 (21%)
		PIKKc_ATR	2285..2559	CDD:270625	57/257 (22%)
		FATC	2605..2636	CDD:280430	8/31 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900