Protein Alignment Treh and Treh

DIOPT Version :10

• Sequence 1: NP_726025.1
• Gene: Treh / 45368
• FlyBaseID: FBgn0003748
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_067456.1
• Gene: Treh / 58866
• MGIID: 1926230
• Length: 576
• Species: Mus musculus
• Alignment Length: 556
• Identity: 240/556 - (43%)
• Similarity: 342/556 - (61%)
• Gaps: 17/556 - (3%)

  Fly    44 EEAQDPFASCKIYCEGNLLHTIQTAVPKLFADSKTFVDMKLNNSPDKTLEDFNAMMEAKNQTPSS 108
            :||..|....:|||.|.|||.:|.|  :|:.|.|.||||.|..|||:.|:.|:.:....|.:...
Mouse    18 QEALPPPCESQIYCHGELLHQVQMA--QLYQDDKQFVDMSLATSPDEVLQKFSELATVHNHSIPK 80

  Fly   109 EDLKQFVDKYFSAPGTELEKWTPTDWKENPSFLDLISDPDLKQWGVELNSIWKDLGRKMKDEVSK 173
            |.|::||..:|...|.||:.|||.|||::|.||..|||.:|:.|..||:.|||.||:|||.||..
Mouse    81 EQLQEFVQSHFQPVGQELQSWTPEDWKDSPQFLQKISDANLRVWAEELHKIWKKLGKKMKAEVLS 145

  Fly   174 NPEYYSIIPVPNPVIVPGGRFIEFYYWDSYWIIRGLLYSQMFDTARGMIENFFSIVNRFGFIPNG 238
            .||..|:|...:|.|||||||:|||||||||::.|||.|:|..|.:||::||..:|..:|.||||
Mouse   146 YPERSSLIYSKHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNG 210

  Fly   239 GRVYYHGRSQPPLLTGMVKSYVDFTNDDKFAIDALDTLEHEFEFFVNNHNVTV----KNHSLCVY 299
            ||:||..||||||||.|:..||..|.|..|..:.:.||..|.:|:..|..|:|    :::.|..|
Mouse   211 GRIYYLQRSQPPLLTLMMDRYVAHTKDVAFLQENIGTLASELDFWTVNRTVSVVSGGQSYVLNRY 275

  Fly   300 RDSSSGPRPESYREDVETGEEFPTDEAKELHYSELKAGAESGMDFSSRWFISPTGTNDGNRSALS 364
            .....||||||||:|.|.....|..: :|..::|||||||||.||||||.:.  |.:....|::.
Mouse   276 YVPYGGPRPESYRKDAELANSVPEGD-RETLWAELKAGAESGWDFSSRWLVG--GPDPDLLSSIR 337

  Fly   365 TTSIVPVDLNAYLYWNAKLIAEFHSKAGNTKKVTEYETKAEKLLLGIQEVLWNEEAGVWLDYDMI 429
            |:.:||.||||:|....:|::.|:|:.||..:.|:|.....:.|..::.|||:|:.|.|.|||:.
Mouse   338 TSKMVPADLNAFLCQAEELMSNFYSRLGNDTEATKYRNLRAQRLAAMEAVLWDEQKGAWFDYDLE 402

  Fly   430 NQKPRDYYTPTNLSPLWVKAFNISESEKISASVMAYIERNKLDSFPGGVPNTLSYTGEQWDAPNV 494
            ..|....:.|:||||||...|:   ...::...:.|:|.:|:.::..|:|.:|..||:|||.||.
Mouse   403 KGKKNLEFYPSNLSPLWAGCFS---DPSVADKALKYLEDSKILTYQYGIPTSLRNTGQQWDFPNA 464

  Fly   495 WAPMQYILVEGLNNLNTPEAKNMSLKWATRWVKTNFAAFSKDRHMYEKYNADEFGVGGGGGEYEV 559
            |||:|.:::.||....:|..:.::.:.|..|:||||..:|:...|:|||:....|..||||||||
Mouse   465 WAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKSAMFEKYDISNGGHPGGGGEYEV 529

  Fly   560 QTGFGWSNGVIIEWLSKHGRDISIGS-----GCGCL 590
            |.||||:||:.:..|.::|..::.|:     |..||
Mouse   530 QEGFGWTNGLALMLLDRYGDQLTSGTQLASLGPHCL 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Treh	NP_726025.1	Trehalase	71..578	CDD:395961	223/510 (44%)
Treh	NP_067456.1	Trehalase	43..548	CDD:395961	222/508 (44%)