Protein Alignment Treh and ntp1

DIOPT Version :10

• Sequence 1: NP_726025.1
• Gene: Treh / 45368
• FlyBaseID: FBgn0003748
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_595086.1
• Gene: ntp1 / 2541115
• PomBaseID: SPBC660.07
• Length: 735
• Species: Schizosaccharomyces pombe
• Alignment Length: 649
• Identity: 150/649 - (23%)
• Similarity: 235/649 - (36%)
• Gaps: 171/649 - (26%)

  Fly    25 TYSLPD------LTTDYNNA-IPVDEEEAQDPFASCKIYCEGNLLHTIQTAVPKLFADSKT---- 78
            ||.|.:      |..||... |.:||....:           |.::.:...:...|.|:.|
pombe   132 TYQLSNLLQELTLAKDYGRRYILLDERRLNE-----------NPVNRLSRLIKGTFWDALTRRID 185

  Fly    79 --FVDMKLNNSPDKTLEDFNAMMEAKNQTPSSEDLKQFVDKYFSAPGTEL------EKWTPTDWK 135
              .:|:...::.|::....|.:...|.:   .|..:.:|......|...|      |:.|| :|.
pombe   186 ASVLDVICRDTKDRSGSHVNRIYVPKAE---QEMYEYYVRAAKERPYLNLQVEYLPEEITP-EWV 246

  Fly   136 ENPSFLDLISDPDLKQWGVELNSIWKDLGRKMKDEVSKNPEYYSIIPVPNPVIVPGGRFIEFYYW 200
            .     |:...|.|....:|          |.:|: ..|.....:     |.:||||||.|.|.|
pombe   247 R-----DVNDKPGLLALAME----------KYQDD-EGNTHLRGV-----PFVVPGGRFNELYGW 290

  Fly   201 DSYWIIRGLLYSQMFDTARGMIENFFSIVNRFGFIPNGGRVYYHGRSQPPLLTGM-VKSYVDFTN 264
            |||:...|||.....|.|:||:|||...:..:|.|.|..|.||..|||||.||.| ::.|....|
pombe   291 DSYFESLGLLVDDRVDLAKGMVENFIFEITYYGKILNANRTYYLLRSQPPFLTDMALRVYERIKN 355

  Fly   265 DDKFAIDALDTLEHEFEFFVNNHNVTVKNH--------------SLCVYRDSSSGPRPESYREDV 315
            ::    .:||.|...|       :.|:|.:              .|..||....|..||:.....
pombe   356 EE----GSLDFLHRAF-------SATIKEYHTVWTATPRLDPKTGLSRYRPGGLGIPPETEASHF 409

  Fly   316 E------------TGEEFP--------TDEAKELHYSELKAGAESGMDFSSRWFISPTGTNDGNR 360
            |            |.|||.        .:.|.:.::...:|..|||.|.:             .|
pombe   410 EHLLRPYMEKYHMTLEEFTHAYNYQQIHEPALDEYFVHDRAVRESGHDTT-------------YR 461

  Fly   361 SALSTTSIVPVDLNAYLYWN----AKLIAEFHSKA-----GNTKKVTEYETKAEKLLLGIQEVLW 416
            .......:..||||:.||..    :.:|.|:....     |..:....::.:|......:::.||
pombe   462 LEKVCADLATVDLNSLLYKYETDISHVILEYFDDKFVLPNGTIETSAIWDRRARARRAAMEKYLW 526

  Fly   417 NEEAGVWLDYDMINQKPRDYYTPTNLSPLWVKAFNISESEK----------ISASVMAYIERNKL 471
            :|...:|.||:...:....|.:.|....||.......::.|          ::..::|
pombe   527 SEADSMWYDYNTKLETKSTYESATAFWALWAGVATPRQAAKFVDVSLPKFEVAGGIVA------- 584

  Fly   472 DSFPGGVPNTLSYTG-----EQWDAPNVWAPMQYILVEGLNNLNTPEAKNMSLKWATRWVKT--- 528
                 |...:|...|     .|||.||.|:|.|.:...||......|.   :.:...||:.|
pombe   585 -----GTKRSLGKVGLDNPSRQWDYPNGWSPQQILAWYGLIRYGYEEE---TRRLVYRWLYTITK 641

  Fly   529 NFAAFSKDRHMYEKYNAD----------EFGVGGGGGEYEVQTGFGWSNG---VIIEWLSKHGR 579
            :|..|  :..:.|||:..          |:|..|...:...:.||||.|.   |.:.:.:.|.|
pombe   642 SFVDF--NGIVVEKYDLTRPVDPHRVEAEYGNQGVNIKGVAREGFGWVNASYEVGLTFCNSHMR 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Treh	NP_726025.1	Trehalase	71..578	CDD:395961	138/593 (23%)
ntp1	NP_595086.1	Trehalase_Ca-bi	89..118	CDD:429490
		Trehalase	146..699	CDD:395961	144/629 (23%)