Protein Alignment Treh and tre-2

DIOPT Version :10

• Sequence 1: NP_726025.1
• Gene: Treh / 45368
• FlyBaseID: FBgn0003748
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_501058.2
• Gene: tre-2 / 177451
• WormBaseID: WBGene00006608
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 226/573 - (39%)
• Similarity: 323/573 - (56%)
• Gaps: 40/573 - (6%)

  Fly    43 EEEAQDPFAS-----------------CKIYCEGNLLHTIQTAVPKLFADSKTFVDMKLNNSPDK 90
            |:|.::|..|                 ..::|:|.|||.:|  :..||.|.||||||.|.:..|.
 Worm    63 EKERREPSTSFSAPFPTSTAFSTKMSPSPVWCDGTLLHAVQ--LSGLFPDCKTFVDMPLKHDADV 125

  Fly    91 TLEDFNAMMEAKNQTPSSED-LKQFVDKYFSAPGTELEKWTPTDWKENPSFLDLISDPDLKQWGV 154
            ||..:||:|..   .|.:.| |..|:.:.|..|..|||:..||||.........|.|.|.:::..
 Worm   126 TLARWNALMAL---APITNDVLALFLRENFDEPEGELEECAPTDWAPMTDQFGGIIDEDYRRFAA 187

  Fly   155 ELNSIWKDLGRKMKDEVSKNPEYYSIIPVPNPVIVPGGRFIEFYYWDSYWIIRGLLYSQMFDTAR 219
            .|::.|..|.||:..:|..|||.|||||||||.:||||||.|.|||||::.|:||:.|.|..|.:
 Worm   188 ALHAKWPTLYRKISKKVRVNPEKYSIIPVPNPFVVPGGRFREMYYWDSFFTIKGLIASGMLTTVK 252

  Fly   220 GMIENFFSIVNRFGFIPNGGRVYYHGRSQPPLLTGMVKSYVDFTNDDKFAIDALDTLEHEFEFFV 284
            |||||...:|..:||||||.||||..||||||||..||:|.:.|.|.:|..|.|.||..||.||.
 Worm   253 GMIENMIYLVETYGFIPNGTRVYYLNRSQPPLLTWCVKAYYEATGDKQFLSDVLPTLRKEFSFFQ 317

  Fly   285 NNHNVTVKNHSLCVYR--DSSSGPRPESYREDVETGEEFPTDEAKELHYSELKAGAESGMDFSSR 347
            .:......:.:..:||  ..:|.|||||||||:|:.|...|.|.|.:.:.:|.|.||||.|||||
 Worm   318 THKTYNHPDWNTPLYRFVVETSHPRPESYREDLESAEHLDTLEKKCVLWGDLAAAAESGRDFSSR 382

  Fly   348 WFISPTGTNDGNRSALSTTSIVPVDLNAYLYWNAKLIAEFHSKAGNTKKVTEYETKAEKLLLGIQ 412
            :| :..|...|..::..|:.::|||||:.:..|.|.::|.::..|:.:....::.:...|...|:
 Worm   383 FF-AVHGPYAGQLASTRTSQLIPVDLNSIICGNMKTLSEMYTVCGDLESAKYFDNEYRTLRDTIR 446

  Fly   413 EVLWNEEAGVWLDYDMINQKPRDYYTPTNLSPLWVKAFNISESEKISASVMA-YIERNKLDSFPG 476
            :||||||...|.|:|:........:..||..|::..:::    |.:.:.|:. |:..:...||||
 Worm   447 QVLWNEEHNCWFDFDVEEGNHATSFHDTNFFPMYCDSYH----EDLDSQVVVDYLTTSGAISFPG 507

  Fly   477 GVPNTLSYTGEQWDAPNVWAPMQYILVEGLNNLNTPEAKNMSLKWATRWVKTNFAAF-SKDRHMY 540
            |:|.:|..:|||||.||.|.|..::|:|||..:...|   ::|....:||:.||..: :....|:
 Worm   508 GIPVSLVNSGEQWDFPNSWPPTTWVLLEGLRKVGQEE---LALSLVEKWVQKNFNMWRTSGGRMF 569

  Fly   541 EKYNADE--FGVGGGGGEYEVQTGFGWSNGVIIEWLSKHGRDI--SIGSGCGC 589
            ||||...  |.| .|||||.:|.||||:||||:::|..:|..|  .:...|.|
 Worm   570 EKYNVVSPCFKV-KGGGEYVMQEGFGWTNGVILDFLKNYGSKIRWQVAESCEC 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Treh	NP_726025.1	Trehalase	71..578	CDD:395961	212/513 (41%)
tre-2	NP_501058.2	Trehalase	107..608	CDD:395961	212/512 (41%)