DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shu and PAS1

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_566993.1	Gene:	PAS1 / 824568	AraportID:	AT3G54010	Length:	635	Species:	Arabidopsis thaliana

Alignment Length:	401	Identity:	79/401 - (19%)
Similarity:	162/401 - (40%)	Gaps:	67/401 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDGEELRSPWTYSFDELRA 76
            |.::||.:.|...:.|.|||:                                   ...|.::|.
plant   235 LTESPLLHIDQDLEEVHFEVE-----------------------------------LVHFIQVRD 264

  Fly    77 LMSEIDENIYKRITRTGHVDREAVP-----NKARVSVRYSGYW--EGETAPFDSSLLRGSK-FVF 133
            ::.  |..:.||..|.|   |...|     ..:|:||.|.|..  |.:|..:||.:....: ..|
plant   265 MLG--DGRLIKRRIRDG---RGEFPMDCPLQDSRLSVHYKGMLLNEEKTVFYDSKIDNNDQPLEF 324

  Fly   134 ETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCPPRIKPKADALFKVEVIDYSLIGDAK 198
            .:|:|.|.||.|:..|.|.|.|.|.........:.:...||.:...|...:::|::.:....|..
plant   325 SSGEGLVPEGFEMCTRLMLPGEIALVTCPPDYAYDKFPRPPGVSEGAHVQWEIELLGFETPRDWT 389

  Fly   199 GIDAIPQEDRDKFCVVYPKAVDLHLHGKDSVKLGRYQSAATAFERAVSSLNYCRMANDEEERKQT 263
            |::         |..:..:|..:...|....|.|:::.|...:|:.:...|:....:::|.:...
plant   390 GLN---------FQSIMDEADKIRSTGNRLFKEGKFELAKAKYEKVLREFNHVNPQDEDEGKIFG 445

  Fly   264 ELLTTLNQNLMIVYNKMNKPKRACIMMKALRHLTMGNPSCKALFQEGRALAALGEYNLARNAY-L 327
            :....|:.|:.....||.:.:::......:.....|:  .|.|::.|.|..|.|||:.|||.: :
plant   446 DTRNMLHLNVAACLLKMGEWRKSIETCNKVLEAKPGH--VKGLYRRGMAYIAGGEYDDARNDFNM 508

  Fly   328 QAQAKQPANKEISDEIISMNKRISKYEEASRDIWARAFSLKNSK-----SDVRKTPAQLEK--EA 385
            ..:..:.:..:.:..::.:.::..:.|..:|..:...|..:..:     |::|:....:|:  |.
plant   509 MIKVDKSSEADATAALLKLKQKEQEAESKARKQFKGLFDKRPGEITEVGSEIREESKTIEEVDET 573

  Fly   386 KEQDFNDKMED 396
            |:.|.::.:|:
plant   574 KDNDDDETLEE 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674	27/100 (27%)
		TPR repeat	218..257	CDD:276809	7/38 (18%)
		TPR repeat	262..295	CDD:276809	4/32 (13%)
		TPR repeat	304..329	CDD:276809	11/25 (44%)
PAS1	NP_566993.1	FKBP_C	44..144	CDD:278674
		FKBP_C	168..257	CDD:302890	8/56 (14%)
		FKBP_C	291..380	CDD:278674	25/88 (28%)
		TPR_11	399..480	CDD:290150	12/80 (15%)
		TPR repeat	437..478	CDD:276809	5/40 (13%)
		TPR_11	451..514	CDD:290150	16/64 (25%)
		TPR repeat	483..511	CDD:276809	11/27 (41%)
		TPR repeat	516..543	CDD:276809	2/26 (8%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810