DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shu and Aipl1

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_067601.1	Gene:	Aipl1 / 59110	RGDID:	70906	Length:	328	Species:	Rattus norvegicus

Alignment Length:	162	Identity:	40/162 - (24%)
Similarity:	68/162 - (41%)	Gaps:	37/162 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 KAVDLHLHGKDS--VKLGRYQSAATAFERAVSSLNYCRMANDEEERKQTEL----LTTLNQNLMI 275
            :||.| |||:.:  .|||||..|||.::.|:..|.     |.:.:.|..|:    |..:...|::
  Rat   176 QAVPL-LHGEGNRLYKLGRYDQAATKYQEAIVCLR-----NLQTKEKPWEVEWLKLEKMINTLIL 234

  Fly   276 VYNKMNKPKRACIMMK------------ALRHLTMGNPS-CKALFQEGRALAALGEYNLARNAYL 327
            .|.:       |::.|            .|||    :|. .||.:...||.|.:.....|:....
  Rat   235 NYCQ-------CLLKKEEYYEVLEHTSDILRH----HPGIVKAYYMRARAHAEVWNAEEAKADLE 288

  Fly   328 QAQAKQPA-NKEISDEIISMNKRISKYEEASR 358
            :....:|: .|.:..|:..:..|::..:|..|
  Rat   289 KVLELEPSMRKAVLRELRLLESRLADKQEEER 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674
		TPR repeat	218..257	CDD:276809	17/40 (43%)
		TPR repeat	262..295	CDD:276809	7/48 (15%)
		TPR repeat	304..329	CDD:276809	6/24 (25%)
Aipl1	NP_067601.1	FKBP_C	30..>89	CDD:302890
		TPR 1	178..211		15/38 (39%)
		TPR_11	180..261	CDD:290150	25/97 (26%)
		TPR repeat	180..224	CDD:276809	17/49 (35%)
		TPR repeat	229..259	CDD:276809	5/36 (14%)
		TPR 2	230..263		8/43 (19%)
		TPR 3	264..297		7/32 (22%)
		TPR repeat	264..292	CDD:276809	6/27 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910