DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shu and Fkbp39

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	64/274 - (23%)
Similarity:	92/274 - (33%)	Gaps:	102/274 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EENFEPYTPQLLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDS----DYEDAL------ 56
            :|:.:..|.:.|.|    |..:|...:.|.|..:.....:...|:|.||    :||..|
  Fly    95 DEDDDQMTIENLLN----SKAIKNSKKSEDDEDENESGEEDEEDTDDDSQIIEEYESFLENGEEE 155

  Fly    57 ---DVD------GEELRSPWTYSFDELRALMSEIDE------------------------NIYKR 88
               |||      |||         ||..:..||.:|                        .:.|:
  Fly   156 DDDDVDEDNEESGEE---------DEQDSDDSEAEEEQPKAKVAKLSPGASAKKSGKEQNGVAKK 211

  Fly    89 -----------------------------------ITRTGHV---------DREAVPNKARVSVR 109
                                               .|.||.|         ..||...| ||||.
  Fly   212 EEAKQQQKKKEKPEAKKEQPKAKEPAKQQPASKDPRTITGGVKIVDQVVGKGEEAKQGK-RVSVY 275

  Fly   110 YSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCPP 174
            |.|..:.....|| |||:|..|.|..|.|.|::|.:|.|..|:...:........:.:|..|.||
  Fly   276 YIGRLQSNNKTFD-SLLKGKPFKFALGGGEVIKGWDVGVAGMKVGGKRVITCPPHMAYGARGAPP 339

  Fly   175 RIKPKADALFKVEV 188
            :|.|.:..:|:||:
  Fly   340 KIGPNSTLVFEVEL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674	33/93 (35%)
		TPR repeat	218..257	CDD:276809
		TPR repeat	262..295	CDD:276809
		TPR repeat	304..329	CDD:276809
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	33/94 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830