DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shu and Fkbp14

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster

Alignment Length:	161	Identity:	47/161 - (29%)
Similarity:	77/161 - (47%)	Gaps:	15/161 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 ENIYKRITRTGHVDREAVPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVA 147
            :::...:..|..|..:...|...:::.|:|..:.:...||||..|...|.|:.|.|.|::|.:..
  Fly    24 QDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQG 88

  Fly   148 VRSMRPYEQAEFIISYKLLFGELGCPPRIKPKADALFKVEVIDYSLIGDA-------KGID--AI 203
            :.:|...|:.:..|..:|.:|:.|....|.|||..||.||:|:   ||:|       |.||  |.
  Fly    89 LLNMCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELIN---IGNAPPTTNVFKEIDDNAD 150

  Fly   204 PQEDRDKFCVV---YPKAVDLHLHGKDSVKL 231
            .|..|::..|.   |.|.....:.|:||.:|
  Fly   151 KQLSREEVIVYVSEYLKKQMTAVEGQDSEEL 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674	28/92 (30%)
		TPR repeat	218..257	CDD:276809	4/14 (29%)
		TPR repeat	262..295	CDD:276809
		TPR repeat	304..329	CDD:276809
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	28/92 (30%)
		EF-hand_7	140..212	CDD:290234	13/42 (31%)
		EFh	141..212	CDD:298682	13/41 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900