DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shu and Fkbp10

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_038942330.1	Gene:	Fkbp10 / 360627	RGDID:	1549751	Length:	620	Species:	Rattus norvegicus

Alignment Length:	161	Identity:	43/161 - (26%)
Similarity:	70/161 - (43%)	Gaps:	21/161 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 VPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYK 164
            |.|...|...|:|.....|| ||||..||..:....|.|.:::|::..:..|.|.|:.:.||...
  Rat   170 VRNSDFVRYHYNGTLLDGTA-FDSSYSRGGTYDTYIGSGWLIKGMDQGLLGMCPGEKRKIIIPPF 233

  Fly   165 LLFGELGC-----PPRIKPKADALFKVEVIDYSLIG-DAKGIDAIPQEDRDKFCVVYPKA----- 218
            |.:||.|.     .|::..:. .||.:..:....:| ...|...:|...    .|:.|:|
  Rat   234 LAYGEKGYGSVWGQPKVGDRG-GLFGMRPLAVPGLGPQMYGSSPVPSPG----TVIPPQASLVFY 293

  Fly   219 ---VDLHLHGKDSVKLGRYQSAATAFERAVS 246
               :|:| :.||:|:|...:.......|||:
  Rat   294 VLLIDVH-NPKDTVQLETLELPQDCVRRAVA 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674	28/93 (30%)
		TPR repeat	218..257	CDD:276809	10/37 (27%)
		TPR repeat	262..295	CDD:276809
		TPR repeat	304..329	CDD:276809
Fkbp10	XP_038942330.1	FKBP_C	54..146	CDD:395196
		FKBP_C	166..297	CDD:395196	34/132 (26%)
		FKBP_C	317..409	CDD:395196	3/7 (43%)
		FKBP_C	430..521	CDD:395196
		EFh	544..605	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900