DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment shu and Fkbp15

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_006538097.1	Gene:	Fkbp15 / 338355	MGIID:	2444782	Length:	1255	Species:	Mus musculus

Alignment Length:	257	Identity:	56/257 - (21%)
Similarity:	98/257 - (38%)	Gaps:	72/257 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 LHG-KDSVKLGRYQSAATAFERAVSSLNYCRMANDEEERKQTELLTTLNQNLMIVYNKMNKPKRA 286
            ||. ::..|:....:||||      .:::.::.....::|:|||...|..||          |..
Mouse   630 LHAEQEKAKVTEELAAATA------QVSHLQLKMTAHQKKETELQLQLTDNL----------KET 678

  Fly   287 CIMMKALRHLTMGNPSCKALFQEGRALAALGEYNLARNAYLQAQAKQPANKEISDEIISMNKRIS 351
            .::.   .|:|             |..|.|.|   .|.|..|.|.|..:.|:...:   :..:::
Mouse   679 DLLR---GHVT-------------RLQADLSE---LREASEQTQTKFKSEKQSRRQ---LELKVT 721

  Fly   352 KYEEASRDIWARAFSLKNSKSDVRKTPA----QLEKEAKE-----QDFNDKMEDLIRRFKNTSDQ 407
            ..||...|:.|...||:.:.|:.:|..|    |.|.|..|     |:..|::..|:::.:.::||
Mouse   722 SLEEELTDLRAEKTSLEKNLSERKKKSAQERCQAEAEMDEIRKSHQEELDRLRQLLKKARVSTDQ 786

  Fly   408 ----------------------QVSFSRKSYSNAQFDATCKLAKEHNLKLTLSPIQEDVLTL 447
                                  |:..|.:.....|:...|.....|..||.|  :|::.|.|
Mouse   787 AAAEQLTLAQAELQSQWEAKCEQLLASARDEHLQQYREVCAQRDAHQQKLAL--LQDECLAL 846

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674
		TPR repeat	218..257	CDD:276809	7/34 (21%)
		TPR repeat	262..295	CDD:276809	7/32 (22%)
		TPR repeat	304..329	CDD:276809	6/24 (25%)
Fkbp15	XP_006538097.1	FKBP_C	192..285	CDD:365980
		PRK10263	<378..>489	CDD:236669
		Smc	<561..890	CDD:224117	56/257 (22%)
		PHA03247	<944..1129	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900