DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shu and Fkbp3

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_038930.1	Gene:	Fkbp3 / 30795	MGIID:	1353460	Length:	224	Species:	Mus musculus

Alignment Length:	189	Identity:	49/189 - (25%)
Similarity:	74/189 - (39%)	Gaps:	44/189 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SYSDLVK----KGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDGEELRSPWTYSFDELRALM 78
            :|:.|.:    ||.|.....|:|.....|..|...||..|:.||      ..|..|:
Mouse    62 AYNHLFESKRFKGTETISKVSEQVKNVKLSDDKPKDSKSEETLD------EGPPKYT-------- 112

  Fly    79 SEIDENIYKRITRTGHVDREAVPNKARVSVRYSGYWEGETAP----FDSSLLRGSK-------FV 132
                    |.|.:.|  |:...|.|..|    ...|...|.|    ||:::...||       ..
Mouse   113 --------KSILKKG--DKTNFPKKGDV----VHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLS 163

  Fly   133 FETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFGELGCP-PRIKPKADALFKVEVID 190
            |:.|.|.|:.|.:.|:.:|...|:|...|..:..:|:.|.| .:|.|....:|:||::|
Mouse   164 FKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNTKLIFEVELVD 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674	29/104 (28%)
		TPR repeat	218..257	CDD:276809
		TPR repeat	262..295	CDD:276809
		TPR repeat	304..329	CDD:276809
Fkbp3	NP_038930.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	88..118		11/51 (22%)
Fkbp3	NP_038930.1	FKBP_C	124..221	CDD:278674	28/100 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900