DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shu and Fkbp7

DIOPT Version :9

Sequence 1:	NP_611837.1	Gene:	shu / 45360	FlyBaseID:	FBgn0003401	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_034352.1	Gene:	Fkbp7 / 14231	MGIID:	1336879	Length:	218	Species:	Mus musculus

Alignment Length:	199	Identity:	47/199 - (23%)
Similarity:	77/199 - (38%)	Gaps:	53/199 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 DSDSDSDYEDALDVDGEELRSPWTYSFDELRALMSEIDENIYKRITRTGHVDREAVPNKARVSVR 109
            |:...:..|...:|..|.|..|                ||..| .:|.|.:          ::..
Mouse    18 DAQGQTKEESTEEVKIEVLHRP----------------ENCSK-TSRKGDL----------LNAH 55

  Fly   110 YSGYWEGETAPFDSSLLRGSKFV------------FETGQGTVVEGLEVAVRSMRPYEQAEFIIS 162
            |.||...:          ||||.            |..|.|.|::||::|:..|.|.|:.:.||.
Mouse    56 YDGYLAKD----------GSKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKRKVIIP 110

  Fly   163 YKLLFGELG-CPPRIKPKADALFKVEVIDYSLIGDAKGIDAIPQEDRDKFCVVYPKAVDLHLHGK 226
            ....:|:.| ...:|.|.|..:|::|:  |::....:.|:...|.|.|....:....::|:|. |
Mouse   111 PSFAYGKEGYAEGKIPPNATLMFEIEL--YAVTKGPRSIETFKQIDTDNDRQLSKAEIELYLQ-K 172

  Fly   227 DSVK 230
            |..|
Mouse   173 DFEK 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:278674	26/105 (25%)
		TPR repeat	218..257	CDD:276809	5/13 (38%)
		TPR repeat	262..295	CDD:276809
		TPR repeat	304..329	CDD:276809
Fkbp7	NP_034352.1	FKBP_C	42..137	CDD:278674	28/115 (24%)
		EF-hand_7	148..210	CDD:290234	8/30 (27%)
		EFh	148..209	CDD:298682	8/30 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	197..218
		Prevents secretion from ER. /evidence=ECO:0000255\|PROSITE-ProRule:PRU10138	215..218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900